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Do older adult cancer survivors experience worse health-related quality of life in comparison to middle-aged cancer survivors? A secondary data analysis of the 2014 behavioral risk factor surveillance study
Abstract
Objectives: The primary aim of this paper was to examine the potential differences in health-related quality of life (HRQOL) between middle-aged (45–64 years old) and older adult (65 years and older) cancer survivors utilizing the contextual model of health-related quality of life.
Methods and Materials: The author conducted a secondary data analysis of the 2014 behavioral risk factor surveillance system cancer survivorship module survey. Only respondents age 45 and older were included, resulting in n = 5656.
Results: Older adult cancer survivors reported significantly better physical and mental HRQOL than middle-aged cancer survivors. In regard to physical HRQOL, respondents who were older adults, employed, completed treatment, and exercised recently were more likely to report good physical HRQOL. Respondents with comorbid conditions and those with greater years since diagnosis were more likely to report poor HRQOL. In regard to mental HRQOL, respondents who were older, married, or had completed treatment were more likely to have good mental HRQOL. Respondents who were unemployed, had experienced financial cost as a barrier to care, had stroke or chronic obstructive pulmonary disorder, or a history of depression were more likely to report poor mental HRQOL.
Conclusion: Older adult cancer survivors experience better mental and physical HRQOL compared to their middle-aged counterparts. Efforts to improve HRQOL in cancer survivors should include middle-aged adults as well as cancer survivors who are unmarried, still in treatment, or have comorbidities. Greater research is needed to better understand how age differentially affects HRQOL in persons with a cancer history.
This paper was published by Scientific Scholar and has been archived here.
References
- Miller KD, Siegel RL, Lin CC, Mariotto AB, Kramer JL, Rowland JH, et al. Cancer treatment and survivorship statistics, 2016. CA Cancer J Clin. 2016;66:271-89.
- Bluethmann SM, Mariotto AB, Rowland JH. Anticipating the “silver tsunami”: Prevalence trajectories and comorbidity burden among older cancer survivors in the United States. Cancer Epidemiol Biomarkers Prev. 2016;25:1029-36.
- Carter J, Stabile C, Gunn A, Sonoda Y. The physical consequences of gynecologic cancer surgery and their impact on sexual, emotional, and quality of life issues. J Sex Med. 2013;10:21-34.
- Duijts SF, van Egmond MP, Spelten E, van Muijen P, Anema JR, van der Beek AJ. Physical and psychosocial problems in cancer survivors beyond return to work: A systematic review. Psychooncology. 2014;23:481-92.
- [CrossRef] [PubMed] [Google Scholar]
- Götze H, Brähler E, Gansera L, Polze N, Köhler N. Psychological distress and quality of life of palliative cancer patients and their caring relatives during home care. Support Care Cancer. 2014;22:2775-82.
- Stanton AL, Rowland JH, Ganz PA. Life after diagnosis and treatment of cancer in adulthood: Contributions from psychosocial oncology research. Am Psychol. 2015;70:159-74.
- Quinten C, Coens C, Ghislan I, Zikos E, Sprangers MA, Ringash J, et al. The effects of age on health-related quality of life in cancer populations: A pooled analysis of randomized controlled trials using the European organization for research and treatment of cancer (EORTC) QLQ-C30 involving 6024 cancer patients. Eur J Cancer. 2015;51:2808-19.
- Champion VL, Wagner LI, Monahan PO, Daggy J, Smith L, Cohee A, et al. Comparison of younger and older breast cancer survivors and age-matched controls on specific and overall quality of life domains. Cancer. 2014;120:2237-46.
- Medina MA, Kennedy BR, Luft CA, Lundberg-Love PK, Galusha JM. Psychological sequelae of cancer in women during the acute phase of survival In: Paludi MA, ed. The Praeger Handbook on Women's Cancers, Personal and Psychological Insights. Santa Barbara, CA: Praeger; 2014.
- Naughton MJ, Weaver KE. Physical and mental health among cancer survivors: Considerations for long-term care and quality of life. N C Med J. 2014;75:283-6.
- Fogerty D, Humes LE, Busey TA. Age-related declines in early sensory memory: Identification of rapid auditory and visual stimulus sequences. Front Aging Neurosci. 2016;8:90.
- Fried LP, Ferrucci L. Etiological role of aging in chronic diseases: From epidemiological evidence to the new geroscience In: Sierra F. Kohanski R, editors. Advances in Geroscience. New York: Springer; 2016. p. :37-51.
- Gadkaree SK, Sun DQ, Li C, Lin FR, Ferrucci L, Simonsick EM, et al. Does sensory function decline independently or concomitantly with age? Data from the Baltimore longitudinal study of aging. J Aging Res. 2016;2016:1865038.
- Milanovic Z, Pantelic S, Trajkovic N, Sporiš G, Kostic R, James N. Age-related decrease in physical activity and functional fitness among elderly men and women. Clin Interv Aging. 2013;8:549-56.
- Prince MJ, Wu F, Guo Y, Gutierrez Robledo LM, O'Donnell M, Sullivan R, et al. The burden of disease in older people and implications for health policy and practice. Lancet. 2015;385:549-62.
- Wilson IB, Cleary PD. Linking clinical variables with health-related quality of life. A conceptual model of patient outcomes. JAMA. 1995;273:59-65.
- Bellizzi KM, Mustian KM, Palesh OG, Diefenbach M. Cancer survivorship and aging: Moving the science forward. Cancer. 2008;113(Suppl 12):3530-9.
- Weaver KE, Forsythe LP, Reeve BB, Alfano CM, Rodriguez JL, Sabatino SA, et al. Mental and physical health-related quality of life among U.S. cancer survivors: Population estimates from the 2010 national health interview survey. Cancer Epidemiol Biomarkers Prev. 2012;21:2108-17.
- Aarts JW, Deckx L, van Abbema DL, Tjan-Heijnen VC, van den Akker M, Buntinx F. The relation between depression, coping and health locus of control: Differences between older and younger patients, with and without cancer. Psychooncology. 2015;24:950-7.
- Nikbakhsh N, Moudi S, Abbasian S, Khafri S. Prevalence of depression and anxiety among cancer patients. Caspian J Intern Med. 2014;5:167-70.
- Avis NE, Levine B, Naughton MJ, Case LD, Naftalis E, Van Zee KJ. Age-related longitudinal changes in depressive symptoms following breast cancer diagnosis and treatment. Breast Cancer Res Treat. 2013;139:199-206.
- Deckx L, van Abbema DL, van den Akker M, van den Broeke C, van Driel M, Bulens P, et al. A cohort study on the evolution of psychosocial problems in older patients with breast or colorectal cancer: comparison with younger cancer patients and older primary care patients without cancer. BMC Geriatr. 2015;15:79.
- Shiraz F, Rahtz E, Bhui K, Hutchison I, Korszun A. Quality of life, psychological wellbeing and treatment needs of trauma and head and neck cancer patients. Br J Oral Maxillofac Surg. 2014;52:513-7.
- Step MM, Kypriotakis GM, Rose JH. An Exploration of the relative influence of patient's age and cancer recurrence status on symptom distress, anxiety, and depression over time. J Psychosoc Oncol. 2013;31:168-90.
- Yang H, Brand JS, Fang F, Chiesa F, Johansson AL, Hall P, et al. Time-dependent risk of depression, anxiety, and stress-related disorders in patients with invasive and in situ breast cancer. Int J Cancer. 2017;140:841-52.
- Siegel RL, Miller KD, Fuchs HE, Jemal A. Cancer statistics 2021. CA Cancer J Clin. 2021;71:7-33.
- Centers for Disease Control and Prevention. Behavioral Risk Factor Surveillance System Overview: BRFSS, 2014. 2015. Atlanta, Georgia, United States: Centers for Disease Control and Prevention; Available from: http://www.cdc.gov/brfss/annual_data/2014/pdf/overview_2014.pdf [Last accessed on 2016 Aug 24]
- Ashing-Giwa KT. The contextual model of HRQoL: A paradigm for expanding the HRQoL framework. Qual Life Res. 2005;14:297-307.
- Ashing-Giwa KT, Tejero JS, Kim J, Padilla GV, Hellemann G. Examining predictive models of HRQOL in a population-based, multiethnic sample of women with breast carcinoma. Qual Life Res. 2007;16:413-28.
- Hennessy CH, Moriarty DG, Zack MM, Scherr PA, Brackbill R. Measuring health-related quality of life for public health surveillance. Public Health Rep. 1994;109:665-72.
- Zhou H, Siegel PZ, Barile J, Njai RS, Thompson WW, Kent C, et al. Models for count data with an application to healthy days measures: Are you driving in screws with a hammer? Prev Chronic Dis. 2014;11:E50. quiz E50
- Andresen EM, Catlin TK, Wyrwich KW, Jackson-Thompson J. Retest reliability of surveillance questions on health related quality of life. J Epidemiol Community Health. 2003;57:339.
- Moriarty DG, Zack MM, Kobau R. The centers for disease control and prevention's healthy days measures population tracking of perceived physical and mental health over time. Health Qual Life Outcomes. 2003;1:37.
- Pierannunzi C, Hu SS, Balluz L. A systematic review of publications assessing reliability and validity of the behavioral risk factor surveillance system (BRFSS), 20014-2011. BMC Med Res Methodol. 2013;13:49.
- Lin YH, McLain AC, Probst JC, Bennett KJ, Qureshi ZP, Eberth JMy. Health-related quality of life among adults 65 years and older in the United States 2011-2012: A multilevel small area estimation approach. Ann Epidemiol. 2017;27:52-8.
- Stenholm S, Westerlund H, Head J, Hyde M, Kawachi I, Pentti J, et al. Comorbidity and functional trajectories from midlife to old age: The health and retirement study. J Gerontol A Biol Sci Med Sci. 2015;70:332-8.
- Loerzel VW, Aroian K. "A bump in the road": Older women's views on surviving breast cancer. J Psychosoc Oncol. 2013;31:65-82.
- Aizer AA, Chen MH, McCarthy EP, Mendu ML, Koo S, Wilhite TJ, et al. Marital status and survival in patients with cancer. J Clin Oncol. 2013;31:3869-76.
- El Ibrahimi S, Pinheiro PS. The effect of marriage on stage at diagnosis and survival in women with cervical cancer. Psychooncology. 2017;26:704-10.
- Leung J, Pachana NA, McLaughlin D. Social support and health-related quality of life in women with breast cancer: A longitudinal study. Psychooncology. 2014;23:1014-20.
- van der Vliet QM, Pereira NR, Janssen SJ, Hornicek FJ, Ferrone M, Bramer JA, et al. What factors are associated with quality of life, pain interference, anxiety, and depression in patients with metastatic bone disease? Clin Orthop Relat Res. 2017;475:498-507.
- Fenn KM, Evans SB, McCorkle R, DiGiovanna MP, Pusztai L, Sanft T, et al. Impact of financial burden of cancer on survivors' quality of life. J Oncol Pract. 2014;10:332-8.
- Kale HP, Carroll NV. Self-reported financial burden of cancer care and its effect on physical and mental health-related quality of life among US cancer survivors. Cancer. 2016;122:283-9.
- Zafar SY, McNeil RB, Thomas CM, Lathan CS, Ayanian JZ, Provenzale D. Population-based assessment of cancer survivors' financial burden and quality of life: A prospective cohort study. J Oncol Pract. 2015;11:145-50.
- Crichton SL, Bray BD, McKevitt C, Rudd AG, Wolfe CD. Patient outcomes up to 15 years after stroke: Survival, disability, quality of life, cognition and mental health. J Neurol Neurosurg Psychiatry. 2016;87:1091-8.
- Sprigg N, Selby J, Fox L, Berge E, Whynes D, Bath PM, et al. Very low quality of life after acute stroke: Data from the Efficacy of Nitric Oxide in Stroke trial. Stroke. 2013;44:3458-62.
- Hines RB, Barrett A, Twumasi-Ankrah P, Broccoli D, Engelman KK, Baranda J, et al. Predictors of guideline treatment nonadherence and the impact on survival in patients with colorectal cancer. J Natl Compr Canc Netw. 2015;13:51-60.
- Huang HL, Kung PT, Chiu CF, Wang YH, Tsai WC. Factors associated with lung cancer patients refusing treatment and their survival: A national cohort study under a universal health insurance in Taiwan. PLoS One. 2014;9:e101731.
- Rieke K, Schmid KK, Lydiatt W, Houfek J, Boilesen E, Watanabe-Galloway S. Depression and survival in head and neck cancer patients. Oral Oncol. 2017;65:76-82.
- Koutoukidis DA, Knobf MT, Lanceley A. Obesity, diet, physical activity, and health-related quality of life in endometrial cancer survivors. Nutr Rev. 2015;73:399-408.
- Spector DJ, Noonan D, Mayer DK, Benecha H, Zimmerman S, Smith SK. Are lifestyle behavioral factors associated with health-related quality of life in long-term survivors of non-Hodgkin lymphoma? Cancer. 2015;121:3343-51.
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Published: 07-02-2022
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