2026-05-17T08:36:58Z https://jmrionline.com/jmri/oai

oai:ojs2.jmrionline.com:article/2 2018-11-29T12:00:30Z jmri:Art driver

Should Research be Made Compulsory in Medical School? Mehta, Varshil Healthcare decision-making is mostly reliant on evidence–based medicine. Building and upgrading skills in scientific reasoning and thinking amongst medical students has now became an important part of medical education. But due to unforeseen reasons, medical students in developing countries have no or very little opportunities to develop research skills and become evidence based physician-scientist. Moreover, there is also an alarming decline in the current number of physician-scientists, which also threatens the progress of translational medicine in the upcoming era. The compulsion of research work in residency, has no doubt, increased the quantity, but the quality has subsided. The only way, to improve the quality of research and medical evidence based health care, is by inculcating various research programs in school and motivating the professors and subsequently, the medical students. Many schools around the world have started various research training programs and the results are astonishing. Hence we suggest, instead of making research compulsory, there should be a location and school based research program which can help in developing interest Medkrux 2017-01-03 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion application/pdf https://jmrionline.com/jmri/article/view/2 10.15419/jmri.2 Journal of Medical Research and Innovation; Vol 1 No 1 (2017); 1-3 2456-8139 eng https://jmrionline.com/jmri/article/view/2/1 Copyright (c) 2017 Varshil Mehta http://creativecommons.org/licenses/by/4.0

oai:ojs2.jmrionline.com:article/3 2018-11-29T12:00:03Z jmri:Art driver

Atlanto-axial subluxation with cervical myelopathy operated with occipital C2 fusion: A case report Kadam, Rahul Bauva, Vishal Shah, Krutarth Yadav, Sunil Background: Atlantoaxial subluxation with cervical myelopathy is a rare condition that can occur mainly by trauma followed by Rheumatoid arthritis, Grisel syndrome, Down’s syndrome and various other metabolic disorders. It is characterized by excessive movement of atlas (C1) over axis (C2) either by bony or ligamentous abnormality. Due to its laxity the spinal cord may get damaged and cause neurologic symptoms. Reduction and fixation is needed for such instability. Case Report: This 55-year-old gentleman was apparently all right 4 years back when he gradually developed difficulty in walking and imbalance. Bilateral Babinski sign was positive, All deep tendon reflexes were brisk; muscle tone was increased with clasp-knife spasticity present in all four limbs. Ankle and patellar clonus was present bilaterally. His X-ray cervical spine showed C1-C2 subluxation in flexion and extension views. Magnetic resonance imaging (MRI) of Cranio-vertebral junction.  Mild subluxation of atlantoaxial joint (3.1 mm) with posterior displacement of dens causing narrowing of bony cervical spinal canal with reduced distance between posterior aspect of dens of C2 and anterior aspect of posterior arch of C1 vertebrae was noticed. Atlas was also slightly displaced anteriorly in relation to baso-occiput. We managed this patient with occipital cervical fusion after reduction from a posterior approach using screws and rods construct and fusion with bone graft from iliac crest. Post operatively the patient was able to walk without any support and tone of the muscles in lower limb decreased, no tingling or numbness are present, no signs of local infection or inflammation. Conclusion: We suggest to operate atlanto-axial subluxation and cervical myelopathy with occipital C2 fusion. Medkrux 2017-01-03 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion application/pdf https://jmrionline.com/jmri/article/view/3 10.15419/jmri.3 Journal of Medical Research and Innovation; Vol 1 No 1 (2017); 4-7 2456-8139 eng https://jmrionline.com/jmri/article/view/3/2 Copyright (c) 2017 Rahul Kadam, Vishal Bauva, Krutarth Shah, Sunil Yadav http://creativecommons.org/licenses/by/4.0

oai:ojs2.jmrionline.com:article/4 2018-11-29T11:58:02Z jmri:Art driver

Emergence of New Risk Factors for causing Hypertension Mehta, Varshil The major risk factors which we have been hearing since decades for causing hypertension are high salt diet, obesity, hyperlipidaemia, age, race, consuming tobacco, sedentary lifestyle, stress, drinking too much alcohol etc. However, there are many studies which shows that sugar, fats and low vitamin d levels are equally responsible for causing hypertension. The article will put forward some interesting points to show that sugars, fats and vitamin d levels equally play an important role in causing hypertension. Medkrux 2017-01-06 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion application/pdf https://jmrionline.com/jmri/article/view/4 10.15419/jmri.4 Journal of Medical Research and Innovation; Vol 1 No 1 (2017); 9-11 2456-8139 eng https://jmrionline.com/jmri/article/view/4/5 Copyright (c) 2017 Varshil Mehta http://creativecommons.org/licenses/by/4.0

oai:ojs2.jmrionline.com:article/8 2018-07-26T21:49:50Z jmri:Art driver

Indian Cancer Congress 2017 Conference Announcement Congress, Indian Cancer TheIndian Cancer Congress (ICC) is an initiative started in 2012 with a vision of providing a common platform for all oncologists in our country as well as South Asia and Asia Pacific region to discuss, deliberate and formulate cancer therapies across these regions. The four major oncology associations (Association of Radiation Oncologists of India, Association of Surgical Oncologists, Indian Society of Medical and Pediatric Oncology and the Indian Society of Oncology) of the country have come together to organize an Indian Cancer congress (ICC) once every four years. Register for the ICC 2017 conference on the website: www.indiancancercongress2017.com Medkrux 2017-01-03 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion application/pdf https://jmrionline.com/jmri/article/view/8 10.15419/jmri.8 Journal of Medical Research and Innovation; Vol 1 No 1 (2017); 8 2456-8139 eng https://jmrionline.com/jmri/article/view/8/4

oai:ojs.pkp.sfu.ca:article/9 2017-04-16T09:20:07Z jmri:CR

oai:ojs2.jmrionline.com:article/10 2018-11-29T11:57:34Z jmri:Art driver

IGF-1 Therapy in Children with Liver Dysfunction Akbar, Anum Ahmad, Ume Salmah Human growth and development occur as a result of numerous processes which gets initiated under the influence of endocrine hormones. Insulin-like growth factor 1 (IGF-1) plays a most pivotal role in the growth and organ development of a child. IGF-1 is a peptide that belongs to somatomedins group of hormones, also known as somatomedin C. It releases from the liver and other tissues under the influence of growth hormone (GH). The liver is the main protagonist source of IGF-1 hence any disease that can cause liver dysfunction will eventually lead to growth impairment. During the period of growth regulation with GH therapy in liver disease and/or post liver transplantation, the persistent deficiency of IGF-1 proves to be a big challenge to therapy. Growth hormone therapy together with IGF-1 infusion can lead to good results on growth. Therefore, it is important to focus on IGF- level in serum along with Growth hormone while treating a child with poor growth in chronic liver disease and after liver transplantation. The role of IGF-1 therapy should also be considered for better growth and development. Medkrux 2017-01-08 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion application/pdf https://jmrionline.com/jmri/article/view/10 10.15419/jmri.10 Journal of Medical Research and Innovation; Vol 1 No 1 (2017); 12-16 2456-8139 eng https://jmrionline.com/jmri/article/view/10/6 Copyright (c) 2017 Anum Akbar, Ume Salmah Ahmad http://creativecommons.org/licenses/by/4.0

oai:ojs2.jmrionline.com:article/15 2018-11-29T11:54:23Z jmri:Art driver

Probiotics: An Adjuvant therapy for D-Galactose induced Alzheimer's disease Mehta, Varshil Bhatt, Kavya Desai, Nimit Naik, Mansi Alzheimer’s disease (AD) is a chronic and slowly progressing neurodegenerative disorder which has become a major health concern worldwide. The literature has shown that oxidative stress is one of the most important risk factors behind the cause of AD. Oxidative stress often leads to the production of Reactive Oxygen Species (ROS). D-Galactose, a physiological nutrient and reducing sugar, non-enzymatically reacts with amines of amino acids in proteins and peptides to form Advanced Glycation End products which activate its receptors coupled to Biochemical pathways that stimulate free radical production and induces mitochondrial dysfunction which damages the neuron intracellularly. High dosage of D-Galactose also suppresses the expression of nerve growth factors and its associated protein which results in the degeneration of nerve cells and reduction of acetylcholine levels in brain regions. This article put forwards the advantages of using Lactic Acid Bacteria (Probiotics) possessing anti-oxidant properties and which produces Acetyl Choline against D-Galactose induced Alzheimer’s disease. Medkrux 2017-03-04 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion application/pdf https://jmrionline.com/jmri/article/view/15 10.15419/jmri.15 Journal of Medical Research and Innovation; Vol 1 No 1 (2017); 30-33 2456-8139 eng https://jmrionline.com/jmri/article/view/15/29 Copyright (c) 2017 Varshil Mehta, Kavya Bhatt, Nimit Desai, Mansi Naik http://creativecommons.org/licenses/by/4.0

oai:ojs2.jmrionline.com:article/16 2018-07-26T21:49:50Z jmri:RTA

Retracted Article: Use of CBCT in Orthodontics- A Review Shah, Dr. Aakash Shah, Dr. Purvesh Goje, Dr. Santosh Kumar Shah, Dr. Romil Modi, Dr. Bhumi The article stands retracted due to double submission by the author Dr. Aakash Shah . It is quite regretful that such authors waste the time and resources of the journal. View the email sent by Dr. Aakash below. Lateral cephalometric radiographs are most commonly used as a diagnostic tool in orthognathic surgery as well as orthodontic treatment. But the limitation of lateral cephalograms is its 2 dimensional nature whereas the human body is 3 dimensional. Conventional 2D lateral cephalograms have numerous drawbacks in terms of investigating the changes in the alveolar bone and roots, particularly in the anterior region, as a consequence of the midsagittal projection. Additionally its accuracy is questionable as it has projection errors. The use of computed tomography in 3D imaging of human body is available in the field of medicine since last 30 years. CT scanning is the three dimensional imaging technique giving quantitative assessments of the buccal and lingual cortical bone plates and labiolingual width of alveolar bone with elevated accuracy and precision. But the use of computed tomography in dentistry is limited because the amount of radiation exposure with this technology is very high. Since the invention of Cone Beam Computed Tomography, the amount of radiation exposure in the patient is reduced. This enhances its use in obtaining the 3D images of the craniofacial structures. This technology helps in visualizing the hard and soft tissues of the craniofacial structures from various perspectives and helps in thorough diagnosis and treatment planning of orthognathic surgery and orthodontic patients. The principles of CBCT and its use in the field of orthodontics will be discussed in detail in this paper. Medkrux 2017-02-04 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion Hall of Shame https://jmrionline.com/jmri/article/view/16 10.15419/jmri.16 Journal of Medical Research and Innovation; Vol 1 No 1 (2017) 2456-8139 en

oai:ojs2.jmrionline.com:article/17 2018-11-29T11:56:21Z jmri:Art driver

Why should you do Research? Mehta, Varshil Chugh, Charvi Pervez, Arshi Today, the world is facing pandemic outburst of diseases. Many Physicians-Scientist are working really hard to find out the measures which can either prevent or cure these diseases. But, we are still lagging behind in one or the other way. The most important way through which we will be able to curb these diseases is by doing Research.  Research is defined as a process of investigation, interpretation and updating of the scientific knowledge. Research is a tool for building knowledge and efficient learning. It is also important for budding and veteran writers, both offline and online. For those looking for a job or a promotion in good hospitals, research is likewise a necessity. It helps in understanding various ongoing health hazards. It is also a way to discard old hypothesis and develop new facts on which the medical world can completely rely on. Research is the need of the day and everyone in medical profession is encouraged to do it including medical students. But their contribution to research is quite less when compared to students of other profession. History says that many inventions were created by medical students. One of the most important research was of insulin discovery and its purification which was made by Dr. Frederick Banting and his second-year medical student assistant Charles Best. Jay Mclean, a medical student from John Hopkins University had discovered Heparin. However, Research should not be made compulsory. Research entails both reading and writing. These two literacy functions help enable computation and comprehension. Without these skills, it is less likely for anyone to appreciate and get involved in research. Reading opens the mind to a vast horizon of knowledge, while writing helps a reader use her/his own perspective and transform this into a more concrete idea that s/he understands. Apart from reading and writing, listening and speaking are also integral in conducting research. Interviews, attending knowledge-generating events, and casual talks with anyone certainly aid in formulating research topics. They can also facilitate the critical thinking process. Listening to experts discuss the merits of their studies helps the listener to analyze a certain issue and write about such analysis. Curiosity may kill not just the cat, but the human as well. Yet, it is the same curiosity that fuels the mind to seek for answers. Indeed, research and doing research encourage people to explore possibilities, to understand existing disorders, and to disclose facts. Without research, healthy life would remain as fantasy. Reading, writing, observing, analyzing, and interacting with others facilitate an inquisitive mind's quest for knowledge and efficient learning. Research serves as an instrument to achieve that healthy world goal. Medkrux 2017-01-30 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion application/pdf https://jmrionline.com/jmri/article/view/17 10.15419/jmri.17 Journal of Medical Research and Innovation; Vol 1 No 1 (2017); 17 2456-8139 eng https://jmrionline.com/jmri/article/view/17/20 Copyright (c) 2017 Varshil Mehta, Charvi Chugh, Arshi Pervez http://creativecommons.org/licenses/by/4.0

oai:ojs.pkp.sfu.ca:article/19 2017-08-06T09:25:51Z jmri:OGA

oai:ojs2.jmrionline.com:article/20 2018-07-26T21:49:50Z jmri:RTA

Retracted Article: Functional Appliances in the Treatment of Class II Malocclusion- A Review Shah, Dr. Aakash Shah, Dr. Purvesh Goje, Dr. Santosh Kumar Shah, Dr. Romil Modi, Dr. Bhumi The article stands retracted due to double submission by the author Dr. Aakash Shah . It is quite regretful that such authors waste the time and resources of the journal. View the email sent by Dr. Aakash below. Functional jaw orthopaedic appliances are a treatment modality for the correction of Class II malocclusions due to mandibular retrusion. A wide range of functional appliances which aim to stimulate mandibular growth by holding the mandible forward is available to correct this type of skeletal and occlusal disharmony. However, the effects of functional appliances are still controversial. Numerous animal experiments and clinical studies have been performed to help ascertain the mechanisms underlying the effects of functional appliances and the optimal timing of treatment. This literature review will be restricted to a discussion of the role of functional appliance therapy in the treatment of class II malocclusions. Medkrux 2017-02-08 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion Hall of Shame https://jmrionline.com/jmri/article/view/20 10.15419/jmri.20 Journal of Medical Research and Innovation; Vol 1 No 1 (2017) 2456-8139

oai:ojs2.jmrionline.com:article/27 2018-11-29T11:58:41Z jmri:Art driver

Health Problems and Health Care Seeking Behaviour of Rohingya Refugees Masud, Abdullah Al Ahmed, Md. Shahoriar Sultana, Mst. Rebeka Alam, S.M. Iftekhar Kabir, Russell Arafat, S.M. Yasir Papadopoulos, Konstantinos Background: Rohingya refugees are one of the most vulnerable group due to lack of health care system, personal hygiene, shelter, sanitation and violence. Aim: The present study aims to find out the health problems and health care seeking behavior of rohingya refugees, to identify the socio-demographic information for such exposure group in relation to age, sex, occupation, living areas, to explore the patient’s physical, emotional, perceptions, attitudes and environmental health problems and to bring out health care seeking behavior of refugees. Methodology: A cross-sectional study was conducted. A total of 149 samples were selected conveniently for this study from the refugee camps. Data was collected by using mixed type of questionnaire. Descriptive statistic was used for data analysis which has depicted through tables, pie chart and bar chart. Results: The finding of the study showed that 45.6% participants had multiple problems, followed by 16.8% participants who had other specific problems like musculoskeletal pain, visual problems and peptic ulcer. Urinary tract infection was the leading individual health problem with 11.4% of the sample group having it. 10.7% participants had hypertension, 6% had respiratory tract infection, 3.4% had nutrition deficiency, 4.75% had diabetes mellitus and 1.3% had sanitation & hygiene problems. Among the participants, 68.4% age ranged between 15-59 years. The study showed that, only 16.1% participants were satisfied with the quality of service they received while 37.6% participants said that they needed better services such as more laboratory test, radiological imaging, more medicine and more doctors. Conclusion: It is clear that refugees suffered from a variety of health problems, because their living condition and environmental situation were not similar like an independent nation. Further, basic amenities like medicines and other services were not available. Medkrux 2017-03-03 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion application/pdf https://jmrionline.com/jmri/article/view/27 10.15419/jmri.27 Journal of Medical Research and Innovation; Vol 1 No 1 (2017); 21-29 2456-8139 eng https://jmrionline.com/jmri/article/view/27/33 Copyright (c) 2017 Abdullah Al Masud, Md. Shahoriar Ahmed, Mst. Rebeka Sultana, S.M. Iftekhar Alam, Russell Kabir, S.M. Yasir Arafat, Konstantinos Papadopoulos http://creativecommons.org/licenses/by/4.0

oai:ojs2.jmrionline.com:article/29 2018-11-29T11:59:07Z jmri:Art driver

Patient Satisfaction in Chamber Setting in Bangladesh measured by Patient-Doctor Relationship Questionnaire (PDRQ-9 Bangla) Arafat, S.M. Yasir Andalib, Amin Shams, Syed Faheem Kabir, Russell Shah, Md. Mohsin Ali Fariduzzaman, A.M. Liton, Mohammad Liakat Ali Ansary, Eusha Ahmad Fidalillah Background: Assessment of patient satisfaction is crucial but there is significant lagging in this sector. Patient satisfaction is an important indicator of health care quality as well as a predictor of treatment adherence. The Good patient-doctor relationship is considered as an integral part of the patient satisfaction. In Bangladesh, this domain is yet to be explored in a large scale. Aim: It was aimed to look into the patient satisfaction level in chamber setting in Bangladesh measured using the patient-doctor relationship questionnaire (PDRQ-9 Bangla). Methods: PDRQ-9 is a short yet excellent tool for assessing the patient-doctor relationship. The data collection was done in private chamber setting by the PDRQ-9 and analyzed. Results: Though the result was not completely in line with the existing literature, the PDRQ-9 was found to be a useful and brief measurement tool in the context of the patient-doctor relationship. Conclusion: Large-scale research in this particular aspect of patient satisfaction in future may provide a more succinct result Medkrux 2017-03-06 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion application/pdf https://jmrionline.com/jmri/article/view/29 10.15419/jmri.29 Journal of Medical Research and Innovation; Vol 1 No 1 (2017); 34-39 2456-8139 eng https://jmrionline.com/jmri/article/view/29/35 Copyright (c) 2017 S.M. Yasir Arafat, Amin Andalib, Syed Faheem Shams, Russell Kabir, Md. Mohsin Ali Shah, A.M. Fariduzzaman, Mohammad Liakat Ali Liton, Eusha Ahmad Fidalillah Ansary http://creativecommons.org/licenses/by/4.0

oai:ojs2.jmrionline.com:article/31 2018-11-29T12:11:53Z jmri:LE driver

Combination of Gemcitabine and Docetaxel in Management of Leiomyosarcoma Metastasis Rajawat, Monali Leiomyosarcoma is a type of a soft tissue sarcoma which is one of the rarest tumor found in the human mankind. It is predominantly localized either in stomach, small intestine or retroperitoneum and often metastasizes to the distant parts like the lungs or liver. The main route of the metastasis is via the bloodstream, however, the lymphatics could also be used as a medium. The etiology of leiomyosarcoma (LMS) is yet unknown to men, but few studies has shown that genetic factors have an important role to play. The treatment options available for LMS metastasis (mets) in liver are very limited which ranges from chemotherapy, radiofrequency ablation and target therapy. Here I discuss a case of LMS mets to the liver managed by a combination therapy of Gemcitabine and Docetaxel. Medkrux 2017-04-14 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion application/xml application/pdf https://jmrionline.com/jmri/article/view/31 10.15419/jmri.31 Journal of Medical Research and Innovation; Vol 1 No 2 (2017); AY1-AY2 2456-8139 eng https://jmrionline.com/jmri/article/view/31/64 https://jmrionline.com/jmri/article/view/31/40 Copyright (c) 2017 Monali Rajawat http://creativecommons.org/licenses/by/4.0

oai:ojs2.jmrionline.com:article/34 2018-11-29T12:01:45Z jmri:Art driver

Dear depression, why do you even exist in the budding medicos? Mehta, Varshil Rajawat, Monali It is a matter of fact that the high demands and pressure of medical school and pre-residency entrance tests pose a tremendous challenge to the personal wellbeing for the physicians in training which leads to high rates of anxiety, burnout, decreased attention, increased incidence of errors, negligence and depression. Medkrux 2017-04-25 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion application/pdf https://jmrionline.com/jmri/article/view/34 10.15419/jmri.34 Journal of Medical Research and Innovation; Vol 1 No 1 (2017); 40-41 2456-8139 eng https://jmrionline.com/jmri/article/view/34/38 Copyright (c) 2017 Varshil Mehta, Monali Rajawat http://creativecommons.org/licenses/by/4.0

oai:ojs2.jmrionline.com:article/35 2018-11-29T12:09:17Z jmri:CR driver

“Let food be your medicine ….” Inclusion of wheat porridge, a whole grain meal, and legumes lowers postprandial glucose in diabetic patient Eapen, John Thottukadavil The present case report shows the importance of a meal consisting of whole grains and legumes in lowering postprandial glycaemia. A diabetic patient decided to try out diet and lifestyle modification to control the hyperglycemia. He incorporated wheat porridge for his breakfast and dinner along with other food. The postprandial glucose came down to 145 mg/dl after three months. To test the efficacy of wheat porridge in controlling the postprandial glycaemia, the intake of wheat porridge was stopped for 7 days. Then the glucose level increased to 231.4 mg/dl. However, the level came down after restarting the intake of wheat porridge (197.5mg/dl). After adding a small quantity of psyllium husk and black gram (a legume), the postprandial glucose came down to163.5 mg/dl, indicating the protective role in lowering postprandial glycaemia. Medkrux 2017-05-09 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion application/xml application/pdf https://jmrionline.com/jmri/article/view/35 10.15419/jmri.35 Journal of Medical Research and Innovation; Vol 1 No 2 (2017); AW1-AW5 2456-8139 eng https://jmrionline.com/jmri/article/view/35/83 https://jmrionline.com/jmri/article/view/35/85 Copyright (c) 2017 John Thottukadavil Eapen http://creativecommons.org/licenses/by/4.0

oai:ojs2.jmrionline.com:article/37 2018-08-04T07:52:20Z jmri:BVA driver

Hiccups in the Neuro-Critical Care Unit: A Symptom Less Studied? Arora, Charu Dutt Wanchoo, Jaya Khera, Garima Background: Hiccups (also referred to as “hiccoughs”) are usually a transient condition that affects almost everyone in their lifetime. However, persistent and intractable hiccups are the types which are often linked with unfavorable outcomes and can also result in respiratory alkalosis in the intubated patients. There is no accurate estimate of the prevalance of hiccups in the patients admitted in the neuro-ICU.The most commonly witnessed hiccups in the neuro-ICU are intractable and neurogenic in nature. In this communication, we discuss the strategy of respiratory care and pharmacological management of hiccups in an adult male post decompressive craniotomy in view of unilateral basal ganglion bleed.  He suffered from persistent hiccups and was managed conservatively with intravenous Metachlorpromide 10 mg on as and when needed (SOS) basis. In conclusion, it seems that persistent and intractable hiccups as a risk factor for ventilator-associated pneumonia in patients who are intubated and mechanically ventilated should be given due attention. We encourage clinical trials in this area of critical care medicine and should also encourage more studies to analyse the effectiveness of non-pharmacological methods. Medkrux 2017-04-10 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion application/xml application/pdf https://jmrionline.com/jmri/article/view/37 10.15419/jmri.37 Journal of Medical Research and Innovation; Vol 1 No 2 (2017); AX1-AX3 2456-8139 eng https://jmrionline.com/jmri/article/view/37/62 https://jmrionline.com/jmri/article/view/37/39 Copyright (c) 2017 Charu Dutt Arora, Jaya Wanchoo; Garima Khera http://creativecommons.org/licenses/by/4.0

oai:ojs.pkp.sfu.ca:article/40 2017-08-06T09:22:51Z jmri:RV

oai:ojs2.jmrionline.com:article/41 2019-02-09T11:20:37Z jmri:Art driver

Universal Health Coverage: A burning need for developing countries Zaman, Sojib Bin Hossain, Naznin The term of universal health coverage (UHC) are getting popularity among the countries who have not yet attained it. Majority of the developing countries are planning to implement the UHC to protect the vulnerable citizen who cannot afford to buy the health services. Poor people living in developing countries, where there is no UHC, are bereft of getting equal health care. They have to bear a significant amount of health cost in buying different services which often causes catastrophic expenditures for an individual and a family. If a country can provide UHC, it will be possible to bring all the citizens under provision of equal and quality care. However, implementation of a UHC is not an easy phenomenon, rather it needs proper design of a good health insurance system by integrating both the public and private health care providers. The influence of good governance and a sustainable health financing system is fundamental to establish UHC in the developing countries. Medkrux 2017-04-17 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion application/pdf https://jmrionline.com/jmri/article/view/41 10.15419/jmri.41 Journal of Medical Research and Innovation; Vol 1 No 1 (2017); 18-20 2456-8139 eng https://jmrionline.com/jmri/article/view/41/49 https://jmrionline.com/jmri/article/view/41/166 Copyright (c) 2017 Sojib Bin Zaman, Naznin Hossain http://creativecommons.org/licenses/by/4.0

oai:ojs.pkp.sfu.ca:article/43 2017-04-18T18:46:08Z jmri:ED

oai:ojs.pkp.sfu.ca:article/44 2017-04-18T18:58:11Z jmri:ED

oai:ojs.pkp.sfu.ca:article/45 2017-04-18T18:55:25Z jmri:OA

oai:ojs.pkp.sfu.ca:article/46 2017-04-18T18:55:21Z jmri:OA

oai:ojs.pkp.sfu.ca:article/47 2017-04-18T19:00:24Z jmri:CR

oai:ojs.pkp.sfu.ca:article/48 2017-04-18T18:54:36Z jmri:RV

oai:ojs.pkp.sfu.ca:article/49 2017-04-18T19:04:02Z jmri:RV

oai:ojs2.jmrionline.com:article/50 2018-11-29T12:02:28Z jmri:OGA driver

Association of Thyroid Stimulating Hormone and Lipid Profile in Pregnancy Mehta, Varshil Pusukuru, Raghuram Ghodke, Babita Introduction: Thyroid hormones have significant functions in embryogenesis and fetal development. Evidence suggests that thyroid stimulating hormone (TSH) may exert extra-thyroidal effects and modify the profile of blood lipids. Aim: To determine the association between maternal blood lipid profile and thyroid stimulating hormone in second and third trimester of pregnancy. Methods & Materials: The present study was carried out at MGM Hospital, Navi Mumbai, India. 200 antenatal cases from October, 2012 to October 2014 were enrolled after taking an informed consent. The blood samples for Thyroid stimulating hormone and lipid profile were taken at 16th and 32nd weeks. Results: The mean TSH level in second trimester was 1.53 mIU/L, with a standard deviation of 1.147 mIU/L. In third trimester, the mean TSH level was increased to 2.60 mIU/L with a standard deviation of 0.836mIU/L. The t-stat value was found to be -10.649 (p < 0.001). In third trimester, TSH was negatively correlated with Cholesterol (r= -0.214, p < 0.01) and VLDL (r= -0.148, p < 0.05). Conclusion: TSH levels rises according to the gestational age, being higher in third trimester as compared to second trimester. There is a significant negative correlation between TSH levels and cholesterol & VLDL in third trimester of the pregnancy. Hence, TSH levels should be looked for, especially in third trimester, in order to keep the thyroid related problems in check. Medkrux 2017-06-28 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion Original Article application/xml application/pdf https://jmrionline.com/jmri/article/view/50 10.15419/jmri.50 Journal of Medical Research and Innovation; Vol 1 No 2 (2017); AU1-AU6 2456-8139 eng https://jmrionline.com/jmri/article/view/50/70 https://jmrionline.com/jmri/article/view/50/68 Copyright (c) 2017 Varshil Mehta, Raghuram Pusukuru, Babita Ghodke http://creativecommons.org/licenses/by/4.0

oai:ojs2.jmrionline.com:article/51 2018-11-23T18:36:07Z jmri:RV driver

Microwave-assisted Eco-Friendly Synthesis and Antimicrobial Evaluation of Aryl-Triazole-1,3,4-Thiadiazols Jaiswal, Shalini Dwivedi, Smriti Due to the growing awareness about environmental pollution and environmental legislation, recent years have witnessed a phenomenal increase in the application of microwave irradiation (MW) in organic synthesis. Heterocyclic compounds are abundant in nature and are of great significance to life because their structural subunits exist in many natural products such as vitamins, hormones, and antibiotics; hence, they have attracted considerable attention in the design of biologically active molecules and advanced organic chemistry. The application of molecular diversity technique to drug discovery is a multidisciplinary effort in organic synthesis. Medicinal chemistry concerns with the discovery, development, interpretation and the identification of mechanism of action of biologically active compounds at the molecular level. Encouraged by above reports and as part of our research programme for development of eco-friendly synthetic protocol for biologically active compounds as well as in pursuing of our work on new solvent-free cyclisation here we report the synthesis of aryl-triazalo -1, 3, 4-thidiazoles. The one-pot reaction of mercapto-s-triazole with aromatic acid using AlCl3 as a catalyst under microwave irradiation (2-3 min) and in solvent-free condition gave aryl-triazalo -1, 3, 4-thidiazoles with improved yield is described here. Medkrux 2017-05-26 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion Review Article application/xml application/pdf https://jmrionline.com/jmri/article/view/51 10.15419/jmri.51 Journal of Medical Research and Innovation; Vol 1 No 3 (2017); 17-22 2456-8139 eng https://jmrionline.com/jmri/article/view/51/91 https://jmrionline.com/jmri/article/view/51/100 Copyright (c) 2017 Shalini Jaiswal, Smriti Dwivedi http://creativecommons.org/licenses/by/4.0

oai:ojs2.jmrionline.com:article/62 2019-02-09T11:17:41Z jmri:RV driver

Contexts and Opportunities of e-Health Technology in Medical Care Zaman, Sojib Bin Hossain, Naznin Ahammed, Shad Ahmed, Zubair Keeping up with a sound health is a fundamental right for the human beings. It also acts as an indicator of the socio-economic development of a country. However, nowadays keeping sound health is challenging because of rapidly increasing non-communicable diseases. Concurrently, we are on the edge of very fast technological advancement which includes usage of cellular technology, high-speed internet and wireless communications. These technologies and their unique applications are creating lots of new dimensions in health care system which is known as e-Health. The medical call centers, emergency toll-free telephone services are being used in all over the world. The newly developed electronic health system can play a vital role in the remote regions of emerging and developing countries although sometimes it seems difficult due to the lack of communication infrastructure. E-Health can be a promising aspect for providing public health benefits if it integrates with the conventional medical system. More strategic approaches are necessary for the planning, development, and evaluation of e-Health. This article is written to depict the existing and future opportunities of e-Health in health support system. Medkrux 2017-05-01 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion Review Article application/xml application/pdf https://jmrionline.com/jmri/article/view/62 10.15419/jmri.62 Journal of Medical Research and Innovation; Vol 1 No 2 (2017); AV1-AV4 2456-8139 eng https://jmrionline.com/jmri/article/view/62/119 https://jmrionline.com/jmri/article/view/62/80 Copyright (c) 2017 Sojib Bin Zaman, Naznin Hossain, Shad Ahammed, Zubair Ahmed http://creativecommons.org/licenses/by/4.0

oai:ojs2.jmrionline.com:article/65 2018-11-29T12:10:08Z jmri:BVA driver

Is Insulin like Growth Factor a new wonder drug? Goel, Shakti Insulin has been used since a long time to treat Diabetes Mellitus. Little is known about the potential new uses of insulin due to its structural similarities with Insulin Like Growth Factors (IGFs). This brief communication aims to throw light on the potential uses of this hormone and its future prospects. Medkrux 2017-04-04 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion application/xml application/pdf https://jmrionline.com/jmri/article/view/65 10.15419/jmri.65 Journal of Medical Research and Innovation; Vol 1 No 2 (2017); AX4-AX6 2456-8139 eng https://jmrionline.com/jmri/article/view/65/79 https://jmrionline.com/jmri/article/view/65/88 Copyright (c) 2017 Shakti Goel http://creativecommons.org/licenses/by/4.0

oai:ojs2.jmrionline.com:article/66 2018-11-29T12:08:24Z jmri:RV driver

Probiotics for Diarrhea in Children Mandal, Anirban Sahi, Puneet Kaur Diarrhea remains the second leading cause of death in children below 5 years of age; in addition it is also the reason for a considerable morbidity in children of all ages throughout the globe. Apart from oral rehydration solution, continued feeding, oral zinc and antibiotics for diarrhea of bacterial etiology, there have been no other proven measures for diarrheal illnesses in children. Probiotics are non-pathogenic live microorganisms. When ingested, probiotics can survive passage through the stomach and small bowel. Probiotics are supposed to have preventive as well as curative effects on several types of diarrhea of different etiologies. Medkrux 2017-05-07 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion Review Article application/xml application/pdf https://jmrionline.com/jmri/article/view/66 10.15419/jmri.66 Journal of Medical Research and Innovation; Vol 1 No 2 (2017); AV5-AV12 2456-8139 eng https://jmrionline.com/jmri/article/view/66/81 https://jmrionline.com/jmri/article/view/66/87 Copyright (c) 2017 Anirban Mandal, Puneet Kaur Sahi http://creativecommons.org/licenses/by/4.0

oai:ojs2.jmrionline.com:article/67 2018-07-12T03:58:54Z jmri:News driver

Teaching Anatomy: need or taste? Farrokhi, Ahmad Soleymani Nejad, Masoume Background: Anatomy is one of the core sections of Basic Medical Sciences. Given the central role of anatomy, the development of medical knowledge and reach new horizons in science is not possible without relying on anatomy. Since in the anatomy science, students are familiar with the basic terms of medical language, the anatomy's hard to know and have a negative attitude towards this course. With these conditions, anatomy professors have an important role in providing incentives for medical students. However, sometimes applying tastes and the entry of too much anatomical detail creates conditions that cut the motivation for medical students. Therefore, this article seeks to offer solutions to cut apply tasteless and coordinate the teaching of anatomy to interest and motivate medical students to increase this lesson. Medkrux 2017-05-02 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion Editorial application/xml application/pdf https://jmrionline.com/jmri/article/view/67 10.15419/jmri.67 Journal of Medical Research and Innovation; Vol 1 No 2 (2017); AT1-AT2 2456-8139 eng https://jmrionline.com/jmri/article/view/67/77 https://jmrionline.com/jmri/article/view/67/82 Copyright (c) 2017 Ahmad Farrokhi, Masoume Soleymani Nejad http://creativecommons.org/licenses/by/4.0

oai:ojs2.jmrionline.com:article/70 2018-06-19T04:16:55Z jmri:ACK

Reviewers Acknowledgement, 1(2), May-August, 2017 [JMRI], Editor The Journal of Medical Research and Innovation would like to thank each and every one who has helped us to review the articles. As a small token of appreciation, we would like to mention the names of all the reviewers in random order here who have reviewed the articles for the May-August, 2017 issue. The list will be updated as when more reviewers review the articles. Varshil Mehta Shakti Goel S.M. Arafat Tushar Kunder Elizabeth KE Mateus De Paula Glehn P.M. Siva Pradeep Jadhav Janice D'sa Arjun Ballal Nishant Gupta Shyam Vora Markus Krings Narayani Srivastava Jagannath Mohan Medkrux 2017-05-01 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion https://jmrionline.com/jmri/article/view/70 10.15419/jmri.70 Journal of Medical Research and Innovation; Vol 1 No 2 (2017); AZ1 2456-8139

oai:ojs.pkp.sfu.ca:article/71 2017-08-02T14:20:13Z jmri:RV

oai:ojs2.jmrionline.com:article/72 2019-02-09T11:25:26Z jmri:OGA driver

An Association of Total Health Expenditure with GDP and Life Expectancy Zaman, Sojib Bin Hossain, Naznin Mehta, Varshil Sharmin, Shuchita Mahmood, Shakeel Ahmed Ibne Introduction: Gradual  total health expenditure (THE) has become a major concern. It is not only the increased THE, but also its unequal growth in  overall economy, found among the developing countries. If increased life expectancy is considered as a leverage for an individual’s investment in health services, it can be  expected that as the life expectancy increases, tendency of health care investment will also experience a boost up. Objective: The aim of the present study was to explore and identify the association of healthcare expenditure with the life expectancy and Gross Domestic Product (GDP) in developing countries, especially that of Bangladesh. Methodology: Data were retrospectively collected from “Health Bulletin 2011” and “Sample Vital Registration System 2010” of Bangladesh considering the fiscal year 1996 to fiscal year 2006. Using STATA, multivariable logistic regression was performed to find out the association of total health expenditure with GDP and life expectancy. Results: A direct relationship between GDP and total health expenditure was found through analysing the data. At the individual level, income  had a direct influence on health spending. However, there was no significant relationship between total health expenditure with increased life expectancy. Conclusion: The present study did not find any association between life expectancy and total health expenditure. However, our analysis found out that total health expenditure is more sensitive to gross domestic product rather than life expectancy. Medkrux 2017-05-12 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion Original Article application/xml application/pdf https://jmrionline.com/jmri/article/view/72 10.15419/jmri.72 Journal of Medical Research and Innovation; Vol 1 No 2 (2017); AU7-AU12 2456-8139 eng https://jmrionline.com/jmri/article/view/72/84 https://jmrionline.com/jmri/article/view/72/86 Copyright (c) 2017 Sojib Bin Zaman, Naznin Hossain, Varshil Mehta, Shuchita Sharmin, Shakeel Ahmed Ibne Mahmood http://creativecommons.org/licenses/by/4.0

oai:ojs2.jmrionline.com:article/74 2019-02-09T11:22:12Z jmri:OGA driver

Impact of Improved Cooking Stove on Maternal Health in Rural Bangladesh: A Quasi-Experimental Study Zaman, Sojib Bin Hossain, Naznin Khandker, Salamat Introduction: Two-thirds of all households in developing countries depend on unprocessed biomass fuel for cooking. Traditional stoves have poor combustion capacity which produce heavy smoke and numerous  harmful pollutants. Switching to Improved Cooking Stove (ICS), a well-designed earthen made stove equipped with a chimney could be beneficial for health. The aim of this study was to assess the efficacy of ICS on maternal health in rural areas of Bangladesh. Methods: A quasi-experimental design was adopted to conduct the study. This study selected 150 Households from 5 villages (intervention) and 150 Households from 2 villages (control) from the Manikgonj District of Bangladesh during January 1, 2012 to July 30, 2012. Differences between control and intervention group were examined by applying t-test or one-way analysis of variance (ANOVA). The conventional cut-off value of 0.05 was taken as statistical significance. Stata (version 13) was used to do the analysis. Results: Most of the respondents (62%) were less than 30 years of age. About 94% participants resided in tin-shaded houses, and 51% kitchens were small. After the intervention period, the measured mean concentrations of Particulate Matter (PM2.5) for the intervention and control group was 259 µg/m3 and 1285 µg/m3, respectively (p<0.05). However, lung function test (LFT) did not reveal significant differences between the two groups (p>0.05). Conclusion: ICS reduced the incidence of respiratory illness among the intervention group, however, did not demonstrate significant changes in LFT during the six months of the follow-up period. Therefore, this study found ICS might have the potential to be used to improve the maternal health in rural Bangladesh. However, more longitudinal investigations are expected to demonstrate the efficacy and impact of ICS on maternal health to support the statement. Medkrux 2017-06-10 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion Original Article application/xml application/pdf https://jmrionline.com/jmri/article/view/74 10.15419/jmri.74 Journal of Medical Research and Innovation; Vol 1 No 3 (2017); 1-9 2456-8139 eng https://jmrionline.com/jmri/article/view/74/95 https://jmrionline.com/jmri/article/view/74/98 Copyright (c) 2017 Sojib Bin Zaman, Naznin Hossain, Salamat Khandker http://creativecommons.org/licenses/by/4.0

oai:ojs2.jmrionline.com:article/75 2018-07-12T03:59:23Z jmri:OGA driver

End Organ Damage in Hypertensive Geriatric Age Group: A Cross Sectional Study Kyada, Prakashkumar Jadhav, Kunal Biswas, T. K. Mehta, Varshil Zaman, Sojib Bin Objective: Hypertension is one of the common risk factors for cardiovascular and cerebrovascular diseases/disorders A developing country like India faces the double burden of communicable and non-communicable diseases; of the which, hypertension is the most important treatable cause of mortality and morbidity with loss of functional capacity and decline in the quality of life. Aim: To study the prevalence of end organ damage in the hypertensive geriatric age group. Method: The present study was a cross sectional study, conducted in 150 elderly patients admitted in MGM Hospital, Navi Mumbai, India with the diagnosis of stage I or II hypertension from 2011 to 2013. Results: Data analysis of the present study showed that 68% of elderly population aged between 60 to 69 years were suffering from hypertension. Compared to males, females had a higher rate of target organ damage. This study found that out of all patients with total end organ damage, 54.6 % had CVS complications, 15.7 % had hypertensive retinopathy, 25.9 % and 18.51 had raised creatinine and proteinuria respectively. 19.4 % had cerebrovascular accident (CVA) complications. Among Cardiovascular related complications Coronary artery disease (CAD) was found in 21 patients, out of them 7 had Congestive cardiac Failure (CCF). Left Ventricular Hypertrophy (LVH) was the most common complication and seen in 38 patients. 13.8 % patients had Regional Wall Motion Abnormality (RWMA) Conclusion: The present study concluded that Isolated Systolic Hypertension (ISH) is the commonest type of hypertension in geriatric age group. This study concluded that the most common risk factors of HTN in the elderly are sedentary life style, dyslipidemia and extra salt intake while the most common end organ damage was observed to be Left Ventricular Hypertrophy followed by renal dysfunction. Medkrux 2017-06-17 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion Original Article application/xml application/pdf https://jmrionline.com/jmri/article/view/75 10.15419/jmri.75 Journal of Medical Research and Innovation; Vol 1 No 3 (2017); 10-16 2456-8139 eng https://jmrionline.com/jmri/article/view/75/93 https://jmrionline.com/jmri/article/view/75/99 Copyright (c) 2017 Prakashkumar Kyada, Kunal Jadhav, T. K. Biswas, Varshil Mehta, Sojib Bin Zaman http://creativecommons.org/licenses/by/4.0

oai:ojs2.jmrionline.com:article/77 2018-07-12T03:59:49Z jmri:RV driver

Is it Difficult to Treat Asthma in Children? Mandal, Anirban Sahi, Puneet Kaur Asthma, the commonest chronic lung disease in childhood, is managed effectively with inhaled medications in most of the cases. But a subset of pediatric asthma patients continues to experience substantial morbidity even after higher doses of medications; they are referred to as problematic severe asthma. In many such cases, the apparent resistance to therapy is actually due to a number of remediable factors. These cases are called ‘difficult to treat asthma’. The physician dealing with a child with problematic severe asthma needs to follow a systematic step- wise approach to find any possible underlying causes of poor response to therapy. The evaluation starts with revisiting the diagnosis of asthma and goes through a checking the prescription, patient compliance, assessment for co-morbidities, environmental triggers and psychological factors. Only in a very small number of cases where no such remediable factors are identified, a diagnosis of severe therapy-resistant asthma is made and the child should be referred to a pediatric pulmonologist for further evaluation and therapy. Medkrux 2017-07-10 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion Review Article application/xml application/pdf https://jmrionline.com/jmri/article/view/77 10.15419/jmri.77 Journal of Medical Research and Innovation; Vol 1 No 3 (2017); 23-30 2456-8139 eng https://jmrionline.com/jmri/article/view/77/96 https://jmrionline.com/jmri/article/view/77/101 Copyright (c) 2017 Anirban Mandal, Puneet Kaur Sahi http://creativecommons.org/licenses/by/4.0

oai:ojs2.jmrionline.com:article/78 2018-02-06T07:30:02Z jmri:ACK

Editors and Reviewers Acknowledgement, 1(3), September-December, 2017 Editorial Team, JMRI The Journal of Medical Research and Innovation would like to thank each and every one who has helped us to review and edit the articles. As a small token of appreciation, we would like to mention the names of all the editors and reviewers in random order here who have edited or reviewed the articles for the September-December, 2017 issue. The list will be updated as when more reviewers review the articles. Editors: Varshil Mehta Shakti Goel Sojib Bin Zaman Reviewers: Varshil Mehta Tushar Kunder Narayani Srivastava Harsha Makwana Charu Dutt Arora Pradeep Jadhav Arjun Ballal Assad Mughal Nasrin Fatahi Medkrux 2017-06-21 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion https://jmrionline.com/jmri/article/view/78 10.15419/jmri.78 Journal of Medical Research and Innovation; Vol 1 No 3 (2017); 37 2456-8139

oai:ojs2.jmrionline.com:article/80 2018-07-12T04:00:43Z jmri:CR driver

Aneurysmal Bone Cyst of Clavicle in a Six-Year-Old Male Child Patel, Rushin P. Goel, Shakti Patel, Pankaj R. Aneurysmal Bone Cyst (ABCs) is a cystic expansile lesion which is usually found in solitary locations in the metaphysis of long bones. The most common locations of ABC are long bones of lower limbs. There is little knowledge about the presence of this tumor in Clavicle. Here we present a case of a six year old male child who presented with complaint of swelling in left shoulder for four months. There was a dilemma in the diagnosis of the swelling due to its unusual presentation and appearance. The Fine Needle Aspiration Cytology was also inconclusive. The diagnosis of ABC was made only by excision biopsy. The Clavicle regenerated to nearly normal anatomy at 15 weeks follow up period. The patient is asymptomatic now and is able to perform all daily activities without any restrictions. The uniqueness of this case lies in the fact that this is the first case where ABC has been reported in Clavicular region in young Asian male of less than 10 years age. Medkrux 2017-07-16 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion application/xml application/pdf https://jmrionline.com/jmri/article/view/80 10.15419/jmri.80 Journal of Medical Research and Innovation; Vol 1 No 3 (2017); 31-36 2456-8139 eng https://jmrionline.com/jmri/article/view/80/97 https://jmrionline.com/jmri/article/view/80/102 Copyright (c) 2017 Rushin P. Patel, Shakti Goel, Pankaj R. Patel http://creativecommons.org/licenses/by/4.0

oai:ojs2.jmrionline.com:article/82 2018-02-06T07:30:02Z jmri:ACK

Best Paper, Reviewer and Editor Awards - 2017 Editorial Team, JMRI The Journal of Medical Research and Innovation would like to thank each and every one who has helped us in any way possible. We really appreciate it and as a token, we would like to present certificates to the authors of the best paper (based on citations and metrics) of the 2017, reviewer (based on the quality and quantity of reviewing the articles for JMRI) and editor (based on the quantity of work shared with the Editor in Chief).E-Certificates of Appreciation shall be sent through emails to the awardees soon.   Best Paper of 2017 Zaman, S., & Hossain, N. (2017). Universal Health Coverage: A burning need for developing countries. Journal Of Medical Research And Innovation, 1(1), 18-20.   Best Editor of 2017 Dr. Shakti Goel   Best Reviewer(s) of 2017 Dr. Arjun Ballal and Dr. Narayani Srivastava Once again, JMRI would like to congratulate the winners. Medkrux 2017-07-19 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion https://jmrionline.com/jmri/article/view/82 10.15419/jmri.82 Journal of Medical Research and Innovation; Vol 1 No 3 (2017); 38 2456-8139

oai:ojs2.jmrionline.com:article/84 2018-07-26T09:02:52Z jmri:News driver

Vegetarian Diet: A Boon or Bane for Health? Mehta, Varshil In recent times, there have been many scientific evidences which suggest that wholesome vegetarian diets offer significant advantages compared to diets containing meat and other foods of animal origin. The benefits ranges from lower intakes of cholesterol, saturated fats, animal proteins and higher intakes of dietary fiber, vitamin C and E, carotenoids, magnesium, folic acid,  and other phytochemicals. However, it is often said that vegetarian diet lacks the nutrients like vitamin B12, proteins, zinc, calcium etc., but if an “Appropriate diet with proper planning” involving supplements is consumed, these deficiencies will never exist. Through the present editorial, I would like to show few benefits of having a vegetarian meal. Medkrux 2017-08-05 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion Editorial application/pdf application/xml https://jmrionline.com/jmri/article/view/e000084 10.15419/jmri.84 Journal of Medical Research and Innovation; Vol 2 No 1 (2018); e000084 2456-8139 eng https://jmrionline.com/jmri/article/view/e000084/104 https://jmrionline.com/jmri/article/view/e000084/103 Copyright (c) 2018 Varshil Mehta http://creativecommons.org/licenses/by/4.0

oai:ojs2.jmrionline.com:article/86 2018-07-12T03:54:25Z jmri:RV driver

ACE Alzheimer’s: The Role of Vitamin A, C and E (ACE) in Oxidative Stress induced Alzheimer’s Disease Mehta, Varshil Desai, Nimit Perwez, Arshi Nemade, Dipali Dawoodi, Sameer Zaman, Sojib Bin Alzheimer's disease (AD), a chronic neurodegenerative disease which is known to progress gradually and has now become a substantial health concern through-out the world. Clinically, cognitive declination and progressive dementia are the main characteristics of AD while pathologically; Aß plaques and tau-neurofibrils are the hallmarks. The present literature search has suggested that oxidative stress is one of the most vital risk factor which can potentially lead to the development of AD. Oxidative stress is known to produce the Reactive Oxygen Species (ROS) which has a potential to increase in the structural and functional abnormalities in the glial cells of the brain and which could further lead to a cognitive decline and subsequently, dementia. Hence, in order to curb this oxidative stress in the glial cells, antioxidants have been proved to be of great help according to the literature search done in PubMed, Google Scholar and Scopus. We included Meta-Analysis, Systemic Reviews and Original studies. Vitamins A, C, and E are an example of antioxidants that can be used as adjuvants in the treatment of AD. This article focuses on the contemporary literature search and presents forward the evidence-based banes of using Vitamin A, C, and E as an adjuvant therapy for preventing and treating AD. Medkrux 2017-10-03 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion Review Article application/pdf application/xml https://jmrionline.com/jmri/article/view/e000086 10.15419/jmri.86 Journal of Medical Research and Innovation; Vol 2 No 1 (2018); e000086 2456-8139 eng https://jmrionline.com/jmri/article/view/e000086/114 https://jmrionline.com/jmri/article/view/e000086/113 Copyright (c) 2018 Varshil Mehta, Nimit Desai, Arshi Perwez, Dipali Nemade, Sameer Dawoodi, Sojib Bin Zaman http://creativecommons.org/licenses/by/4.0

oai:ojs2.jmrionline.com:article/87 2018-09-08T12:53:23Z jmri:News driver

Humility: A Key to get Published Goel, Shakti Humility has been little understood despite being an important part of the scientific writing. Many manuscripts with good data remain unpublished due to their lack of humility leading to repeated rejections. This Editorial aims to highlight the importance of humble writing and how it can be incorporated by authors it in their scientific methodology. Medkrux 2017-09-15 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion Editorial application/pdf application/xml https://jmrionline.com/jmri/article/view/e000087 10.15419/jmri.87 Journal of Medical Research and Innovation; Vol 2 No 1 (2018); e000087 2456-8139 eng https://jmrionline.com/jmri/article/view/e000087/110 https://jmrionline.com/jmri/article/view/e000087/109 Copyright (c) 2018 Shakti Goel, MBBS, MS http://creativecommons.org/licenses/by/4.0

oai:ojs2.jmrionline.com:article/88 2019-02-09T11:22:39Z jmri:OGA driver

Access to Water and Awareness about the Unsafe Water in Rural Bangladesh Chowdhury, Fahim Subhan Zaman, Sojib Bin Mahmood, Shakeel Ahmed Ibne Introduction: Access to drinking water is a fundamental concern for many countries, including Bangladesh. Drinking of unsafe water might result to cause diseases and illness which heightens the economic burden for every one by increasing the treatment costs and work days lost. In Bangladesh, rural households coupled with the lack of safe water, also faces water-contamination with arsenic and other pollutants. Objective: This study explores the status of the rural people in accessing the water for households. It also determines their knowledge regarding the contaminated water. Methodology: The current study used retrospective data from Bangladesh Rural Advancement Committee’s (BRAC) Research and Evaluation Division’s baseline survey which was initiated under the ‘water, sanitation and hygiene’ program. Data was taken from 16,052 households between November 2006 and June 2007. Descriptive statistics were used to report the study findings. Results: Approximately 67% of the households had a permanent water source and majority had their deep tube well. A major proportion of the household respondent (70%) identified the method properly to purify polluted water. About 41% households used tube well as a source of water for daily purposes, i.e., drinking, cooking, washing utensils, and bathing. Majority (85%) of the households were found to pay willingly for a good source of water. Households with the non-governmental organization (NGO) membership were willing to pay even more for the safe water as compared to households without NGO membership. Conclusion: Respondents had considerable knowledge and awareness concerning the contaminated water. The association of NGO membership and level of awareness presented in this study should be of particular interest to the policy makers. Keywords:  Health, Awareness, Knowledge, Rural Bangladesh. Medkrux 2017-09-09 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion Original Article application/pdf application/xml https://jmrionline.com/jmri/article/view/e000088 10.15419/jmri.88 Journal of Medical Research and Innovation; Vol 2 No 1 (2018); e000088 2456-8139 eng https://jmrionline.com/jmri/article/view/e000088/107 https://jmrionline.com/jmri/article/view/e000088/108 Copyright (c) 2018 Fahim Subhan Chowdhury, Sojib Bin Zaman, Shakeel Ahmed Ibne Mahmood http://creativecommons.org/licenses/by/4.0

oai:ojs2.jmrionline.com:article/91 2018-07-12T03:56:39Z jmri:ANV driver

Ilizarov in Distal Radial Fractures Prakash, Lakshmanan Fracture dislocations around the wrist are managed either by scaffolding it with a plaster or with internal fixation devices. The present video below presents forward a third option i.e. Closed ligamentotaxis with ilizarov frame. This is an extremely simple, atraumatic and wonderful solution. Medkrux 2017-08-31 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion application/xml https://jmrionline.com/jmri/article/view/e000091 10.15419/jmri.91 Journal of Medical Research and Innovation; Vol 2 No 1 (2018); e000091 2456-8139 eng https://jmrionline.com/jmri/article/view/e000091/106 Copyright (c) 2018 Lakshmanan Prakash, MS http://creativecommons.org/licenses/by/4.0

oai:ojs2.jmrionline.com:article/95 2018-07-12T03:55:55Z jmri:CR driver

Henoch-Schonlein Purpura Successfully Treated with Dexamethasone: A Case Report of Six-Year-Old Female Adhikari, Purushottam Henoch-Schonlein Purpura (HSP) is one of the most common causes of small vessel vasculitis in children.  A six-year-old female presented with abdominal pain, swelling and rashes over both the legs associated with multiple episodes of vomiting for around ten days. Stool for the occult blood test was positive but there was an absence of hematuria and albuminuria. The case was diagnosed as HSP and treated with dexamethasone for ten days. The patient was finally discharged on the resolution of her symptoms.  Early diagnosis and treatment favor the better outcome in cases without any renal complications. Medkrux 2017-11-01 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion application/pdf application/xml https://jmrionline.com/jmri/article/view/e000095 10.15419/jmri.95 Journal of Medical Research and Innovation; Vol 2 No 1 (2018); e000095 2456-8139 eng https://jmrionline.com/jmri/article/view/e000095/117 https://jmrionline.com/jmri/article/view/e000095/118 Copyright (c) 2018 Purushottam Adhikari http://creativecommons.org/licenses/by/4.0

oai:ojs2.jmrionline.com:article/97 2018-07-12T03:56:13Z jmri:BVA driver

Students' Engagement during Collection of Attendance: An Experience of a Pilot Study Mondal, Himel Mondal, Shaikat In many medical colleges in India, the annual intake for an undergraduate course is 250. Recording attendance of 250 students is a humongous task. It involves an average of 8.93 ± 1.06 minutes, which is approximately 15% of the total time of the one-hour lecture. During this time, students commonly sit idly while waiting for their roll number call. Interestingly, continuous calling of 250 roll numbers at a stretch is an additional voice stress to the teachers. With this background, we designed a program – students’ engagement during collection of attendance (SEdCA). A comprehension test about the lecture topic was conducted in five minutes, and the answer sheets were collected in the next three minutes. These answer sheets were then scanned (i.e., looked at all parts of answer sheets) for roll numbers and were recorded in the register. This method keeps the students engaged in an academic activity during the time of attendance recording. It also helps in reduction of voice stress to the teachers. This method of attendance collection may be adapted by institutions according to available logistics especially when their student’s strength is more than 250. Medkrux 2017-10-23 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion application/pdf application/xml https://jmrionline.com/jmri/article/view/e000097 10.15419/jmri.97 Journal of Medical Research and Innovation; Vol 2 No 1 (2018); e000097 2456-8139 eng https://jmrionline.com/jmri/article/view/e000097/115 https://jmrionline.com/jmri/article/view/e000097/116 Copyright (c) 2018 Himel Mondal, Shaikat Mondal http://creativecommons.org/licenses/by/4.0

oai:ojs2.jmrionline.com:article/100 2018-11-02T10:21:31Z jmri:OGA driver

Prognostic importance of acute heart failure persistence in patients with ST-elevation myocardial infarction Kozhukhov, Sergey Parkhomenko, Alexander Dovganych, Nataliia Introduction: Acute heart failure (AHF) is one of the most frequent complication of acute myocardial infarction (AMI). It is not only associated with a several-fold increase of in-hospital mortality but also, worsens the long-term survival in comparison to those without AHF. The AHF is observed to be more in AMI patients whose in-hospital stay is more than 3 days. The clinical implications and prognostic accuracy of the AHF term in the setting of AMI are yet unknown. Methods: We observed 1,104 consecutive cardiac care patients, who were admitted with ST-elevation AMI (STEMI). They were divided into groups according to the AHF presence {AHF(+) n=334 and AHF(-) n=764}. Among 334 AHF(+) patients: 252 patients were found to have a transient AHFt(+), whereas 82 of AHF(+) patients had persistent AHFp(+) during in-hospital period.  Patients' baseline characteristics, blood analysis, left ventricle (LV) and renal function data were assessed and analyzed on the admission day and 10th day post-admission. The follow-up was conducted on the 30th day and after 2 years. Results. STEMI patients accompanied by AHF(+) were older, presented mostly with anterior AMI (p<0.01), had lower LV ejection fraction (EF) (p<0.01) and a higher heart rate (p<0.05). Their rates of comorbidities and of in-hospital complications such as recurrent angina, reinfarction, LV aneurism were higher in comparision to AHF(-) patients. AHFp(+) patients had the shortest time from symptoms onset before thrombolysis in comparision to AHFt(+) and AHF(-) groups. Partial recovery of cardiac function according to Left ventricular ejection fraction (LVEF) and end-systolic volume index, occurred mainly in AHF(-) and AHFt(+) patients on the 10th day post-admission, but not in AHFp(+). STEMI patients with AHFp(+) demonstrated a larger infarct size, higher C-reactive protein and VGEF level, fasting glucose and heart rate on admission, higher erythrocyte sedimentation rate, absence of heart rate normalization on the 10th day post-admission. All of these markers were the signs of severe myocardial damage and inflammation, which can reflect worse recovery in AHF patients despite optimal management. Patients with AHF(+) had renal dysfunction on admission while its creatinine clearance (CrCl) decreased during the in-hospital period which is the reflection of a poor prognosis. Сardiovascular mortality and non-fatal MI were significantly higher in the AHFp(+) group as compared to the AHFt(+) and the AHF(–) groups during the 30 days and 2 years of follow-up. Conclusion: The AHF is a frequent STEMI complication. AHF lasting >3 days had worse short- and long-term prognosis. Therefore, an aggressive strategy should be recommended particularly in patients who have clinical signs and symptoms of persistent AHF. Medkrux 2018-01-02 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion Original Article application/pdf application/xml https://jmrionline.com/jmri/article/view/100 10.15419/jmri.100 Journal of Medical Research and Innovation; Vol 2 No 1 (2018); e000100 2456-8139 eng https://jmrionline.com/jmri/article/view/100/129 https://jmrionline.com/jmri/article/view/100/124 Copyright (c) 2018 Sergey Kozhukhov, Alexander Parkhomenko, Nataliia Dovganych http://creativecommons.org/licenses/by/4.0

oai:ojs2.jmrionline.com:article/101 2018-11-02T10:21:31Z jmri:OGA driver

Clinical Profile of Ascites Based on Presentation and Laboratory Findings: An institutional experience from Kathmandu, Nepal Joshi, Rinku Shrestha, Dhan Bahadur Pande, Rajib Maharjan, Sukriti Introduction: Ascites is the fluid collection in the potential space of the peritoneal cavity. Alcoholic liver disease and intra-abdominal malignancy are two major etiologies behind it. Also, diagnosis of tuberculous ascites should be thought of due to endemicity. Cirrhotic patients at any time during the course of disease, invariably present with ascites which is one of the marker of decompensation. In our context, etiology behind ascites and its correlation with symptoms and clinical findings not yet studied, so present study is conceptualized. Methods:This is a cross-sectional retrospective descriptive hospital based record review of patients presented with ascites in a tertiary center of Kathmandu. One hundred fourteen patients with ascites under regular follow up of Shree Birendra Hospital (SBH) were reviewed. Data regarding presenting complaints, examination findings, relevant investigations during first visit and final diagnosis were retrieved from our own record keeping and recorded information were then evaluated. Results: Patients having ascites have myriad of symptoms and signs, commonest clinical feature being icterus (74, 64.9%). Most of them were anemic at presentation. Forty-two (36.8%) had high blood urea and 36 (31.5%) with high creatinine suggesting approximately 30-40% cases presented with deranged renal function test. Ninety-three (81.5%) had raised total serum bilirubin. Similarly, PT/INR derangements were in 74 (64.9%) and 57 (50%) suggesting deranged liver function. Serum albumin was less than 3.5 gram/deciliter in 83(72.8%) cases. Among the patients studied, 80 (70.1%) had high Serum-Ascites Abumin Gradient (SAAG) suggesting transudative type of ascites and rest 34 had low SAAG suggesting exudative type of ascites. Overall assessment revealed, majority of patients (71.05%) had Chronic liver disease (CLD) as the cause of ascites. Conclusions: Ascites due to chronic liver disease was the main finding with etiology supported by laboratory findings. Significant numbers of the patients had deranged renal function on top of liver function derangement, so these parameters need to be properly taken care of. Key Words: Ascites, liver cirrhosis, serum ascetic albumin gradient. Medkrux 2018-01-02 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion Original Article application/pdf application/xml https://jmrionline.com/jmri/article/view/101 10.15419/jmri.101 Journal of Medical Research and Innovation; Vol 2 No 1 (2018); e000101 2456-8139 eng https://jmrionline.com/jmri/article/view/101/130 https://jmrionline.com/jmri/article/view/101/128 Copyright (c) 2018 Rinku Joshi, Dhan Bahadur Shrestha, Rajib Pande, Sukriti Maharjan http://creativecommons.org/licenses/by/4.0

oai:ojs2.jmrionline.com:article/106 2018-12-22T13:32:06Z jmri:FWD driver

Welcome to volume 2 of Journal of Medical Research and Innovation Mehta, Varshil It is my pleasure to introduce the first issue of volume 2 from Journal of Medical Research and Innovation (JMRI). The entire JMRI team is excited to begin our second year journey of publishing good quality-research from across all the medical-related disciplines, all the way from the bench to the bedside. Although we have some quite interesting things planned for 2018, in this Foreword, we will have a look back over some important highlights from volume 1 and some achievements of JMRI from the year 2017. Medkrux 2017-12-09 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion application/pdf application/xml https://jmrionline.com/jmri/article/view/106 10.15419/jmri.106 Journal of Medical Research and Innovation; Vol 2 No 1 (2018); e000106 2456-8139 eng https://jmrionline.com/jmri/article/view/106/131 https://jmrionline.com/jmri/article/view/106/120 Copyright (c) 2018 Varshil Mehta http://creativecommons.org/licenses/by/4.0

oai:ojs2.jmrionline.com:article/108 2018-11-02T10:21:31Z jmri:CR driver

Valproic Acid-Induced Hyperammonemia with Encephalopathy (VIHE): A Case Report Sattar, Yasar Merotto, Benjamin Dedousis, Anthony Aadil, Muhammad Zil-E-Ali, Ahsan Valproic acid (VPA) is a wide spectrum antiepileptic medication indicated for seizure prophylaxis across the spectrum of epilepsy. Since coming into clinical use, VPA has also been recommended for the management of a variety of other pathologies, including, most notably, mood stabilization in the manic patient. VPA’s common adverse effects include gastrointestinal, influenza-like symptoms, headache, and difficulties with sleep; nonetheless, in rare instances, VPA has been noted to cause the severe and potentially lethal condition of hyperammonemia with encephalopathy (VIHE). VIHE is the result of a dose-independent increase in ammonia levels. Often the patient is asymptomatic; if symptoms reach clinical threshold, lethargy is most common, though seizures, focal neurologic deficits and even coma are possible. VIHE can occur in patients despite normal hepatic function, normal loading doses, chronic stable doses and normal free serum drug levels. Once the diagnosis is confirmed, the first approach for symptomatic patients is to discontinue VPA, start alternative mood stabilizer as indicated, and supplement hyperammonemia treatment with lactulose, carnitine or carglumic acid. Below is a case report of VIHE that developed in an adolescent girl with a history of Bipolar I Disorder who was hospitalized in our facility for stabilization of mania.  As demonstrated below, early diagnosis of VIHE is pivotal in reducing morbidity and ultimately can be life-saving. Medkrux 2018-01-28 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion application/pdf application/xml https://jmrionline.com/jmri/article/view/108 10.15419/jmri.108 Journal of Medical Research and Innovation; Vol 2 No 1 (2018); e000108 2456-8139 eng https://jmrionline.com/jmri/article/view/108/125 https://jmrionline.com/jmri/article/view/108/127 Copyright (c) 2018 Yasar Sattar, Benjamin Merotto, Anthony Dedousis, Muhammad Aadil, Ahsan Zil-E-Ali http://creativecommons.org/licenses/by/4.0

oai:ojs2.jmrionline.com:article/109 2018-11-14T08:15:46Z jmri:CR driver

Presentation with Personality changes and Tinnitus to a Vascular Intervention: Rare case of Carotid Body Paraganglioma Zil-E-Ali, Ahsan Ahmed, Zubair Faquih, Amber Ehsan Ishaq, Muhammad Aadil, Muhammad Background: Carotid body paragangliomas are rare neuroendocrine neoplasms of chromaffin negative glomus cells. This case report explains an atypical case with unusual presentation and treatment. Case Report: A healthy smoker technician by profession was brought to the emergency room (ER) with coprolalia. The general physical exam did not reveal any information. His history revealed unilateral tinnitus and odynophagia leading to a consultation by the neurologist with head imaging. Acoustic neuroma was ruled out and the caregiver was asked to elaborate the events mentioned in the history and a psychiatric examination was done. The personality changes were evaluated by the psychiatrist that showed overlapping of delirium and depression. The patient was further examined by a vascular surgeon. After careful revisiting of the history, examination and indication of tender mass in the neck by the patient's vascular surgeon, the diagnosis of carotid body paraganglioma was made which was followed by surgical resection for treatment. Conclusion: Carotid Body Paragangliomas are very vascular structures and their manipulation in a surgery setting requires expertise. This case presented with personality changes and tinnitus, a very less likely event to occur in a carotid body tumor. The present care report, thus adds on to the literature of carotid body tumors and its presenting symptoms. Medkrux 2018-03-19 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion application/pdf application/xml https://jmrionline.com/jmri/article/view/109 10.15419/jmri.109 Journal of Medical Research and Innovation; Vol 2 No 2 (2018); e000109 2456-8139 eng https://jmrionline.com/jmri/article/view/109/135 https://jmrionline.com/jmri/article/view/109/134 Copyright (c) 2018 Ahsan Zil-E-Ali, Zubair Ahmed, Amber Ehsan Faquih, Muhammad Ishaq, Muhammad Aadil http://creativecommons.org/licenses/by/4.0

oai:ojs2.jmrionline.com:article/110 2018-11-02T10:21:31Z jmri:ACK

Editors and Reviewers Acknowledgement, 2(1), January-June, 2018 Team, Editorial The Journal of Medical Research and Innovation would like to thank each and every one who has helped us to review and edit the articles. As a small token of appreciation, we would like to mention the names of all the editors and reviewers in random order here who have edited or reviewed the articles for the January-June, 2018 issue. The list will be updated as when more reviewers review the articles. Editors 1) Varshil Mehta2) Shakti Goel3) Surya Parajuli4) Nikhil Nalluri5) Vitaliy Bezsheiko Reviewers 1) Shakti Goel 2) Assad Mughal 3) Harsha Makwana 4) Megha Patel 5) Ishpreet Biji 6) Surya Parajuli 7) Varshil Mehta 8) Heera KC 9) Prem Bhattarai 10) Tushar Kunder 11) Akshay Avula 12) Mykola Khaitovych 13) K Bedmutha 14) Mayank Jain 15) Joseph Bell 16) Vitaliy Bezsheiko 17) Ahmad Farrokhi 18) N. Kumar Medkrux 2018-01-16 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion https://jmrionline.com/jmri/article/view/110 10.15419/jmri.110 Journal of Medical Research and Innovation; Vol 2 No 1 (2018); e000110 2456-8139 Copyright (c) 2018 Editorial Team http://creativecommons.org/licenses/by/4.0

oai:ojs2.jmrionline.com:article/111 2018-11-14T08:15:46Z jmri:OGA driver

Demographic Profile of Spinal Cord Injury Patients Admitted in a Rehabilitation Centre: An Observational Study from Bangladesh Rahman, Ziniya Mustary Alam, S. M. Goni, Md. Shujayt Ahmed, Faruq Tawhid, A K M Ahmed, Md. Shahoriar Background:  Spinal cord injury (SCI) is a life threating condition which has a profound impact in the morbidity and mortality. SCI causes lifetime sufferings and mostly occur among the young adults. Not only in Bangladesh but also worldwide, SCI is a devastating and burdensome condition. This research was conducted to see the demographic profile of SCI patients in Bangladesh. Methods and Materials: This is a retrospective analysis where data was collected from medical records of all SCI patients admitted in between January 2012 to December 2014 from Centre for the Rehabilitation of the Paralysed (CRP), Savar. Results: A total of 1172 SCI patients were analyzed. Most of the patients were in their second to third decade of life which consisted 28.8% (n=338). Among total respondents, 86.2% (n=1010) were male and 13.8% (n=162) were female. Most of the participants 61.1% (n=716) were from rural area. The main cause of SCI was fall from height (FFH) {45.8% (n = 537)} followed by the road traffic accidents (RTA) {24.7% (n = 288)}. Overall, 52.3% (n = 613) of participants suffered from traumatic paraplegia while 60.9% (n = 714) had complete lesion. Among the total participants, 30.70% (n = 359) of participants had skeletal level C1-C7 injury. Division-wise distribution shows that FFH is a major cause of SCI {14.84% (n = 174)} followed by the RTA which is a second most common cause in 8.95% (n = 105) of participants in Dhaka division while SCI due to bull attacks and bullet injury are a major cause in Khulna division {1.02% (n = 12)} and Chittagong division respectively. Conclusion: The data is collected from a tertiary level of rehabilitation centre where extensive demographic data was not previously represented. In many developing countries SCI is neglected, poorly managed and deprived from society. In addition, the present study suggests that demographic factors may affect the characteristics of SCI. Medkrux 2018-03-01 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion Original Article application/pdf application/xml https://jmrionline.com/jmri/article/view/111 10.15419/jmri.111 Journal of Medical Research and Innovation; Vol 2 No 2 (2018); e000111 2456-8139 eng https://jmrionline.com/jmri/article/view/111/132 https://jmrionline.com/jmri/article/view/111/133 Copyright (c) 2018 Ziniya Mustary Rahman, S. M. Alam, Md. Shujayt Goni, Faruq Ahmed, A K M Tawhid, Md. Shahoriar Ahmed http://creativecommons.org/licenses/by/4.0

oai:ojs2.jmrionline.com:article/115 2018-11-14T08:15:46Z jmri:LE driver

A Rare Pulmonary Manisfestation of Kahler's disease Baheti, Gaurav Jain, Ankur Medkrux 2018-04-20 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion application/xml application/pdf https://jmrionline.com/jmri/article/view/115 10.15419/jmri.115 Journal of Medical Research and Innovation; Vol 2 No 2 (2018); e000115 2456-8139 eng https://jmrionline.com/jmri/article/view/115/136 https://jmrionline.com/jmri/article/view/115/138 Copyright (c) 2018 Gaurav Baheti, Ankur Jain http://creativecommons.org/licenses/by/4.0

oai:ojs2.jmrionline.com:article/116 2018-11-14T08:15:46Z jmri:News driver

Proposing the concept of Perfection Quotient (PQ) as a measure of readiness for health behavior change Sharma, Manoj Intelligence Quotient (IQ) has been used for a long time to test for readiness of individuals with regard to their learning abilities.  It offers limited utility in ascertaining readiness toward health behavior change.  Work on emotional quotient (EQ) and X quotient (XQ) has been done in recent years but has not been applied for determining readiness toward health behavior change through health education and health promotion interventions.  The purpose of this editorial is to propose a novel concept of perfection quotient (PQ) that integrates IQ, EQ and XQ for ascertaining the readiness for health behavior change through health education and health promotion interventions in a variety of target populations. Such measure will be invaluable in ameliorating the impact of health education and health promotion interventions. Medkrux 2018-04-20 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion Editorial application/xml application/pdf https://jmrionline.com/jmri/article/view/116 10.15419/jmri.116 Journal of Medical Research and Innovation; Vol 2 No 2 (2018); e000116 2456-8139 eng https://jmrionline.com/jmri/article/view/116/137 https://jmrionline.com/jmri/article/view/116/139 Copyright (c) 2018 Manoj Sharma http://creativecommons.org/licenses/by/4.0

oai:ojs2.jmrionline.com:article/119 2018-11-14T08:15:46Z jmri:OGA driver

Hydroelectrophoresis for Transdermal Administration of Verapamil or of Hyaluronic Acid in Peyronie's Disease: A Prospective, Open Label, Multicenter Study Cavallini, Giorgio Maretti, Carlo Aim & Objective: To assess the efficacy of a new electromotive system for the transcutaneous delivery of verapamil or of hyaluronic acid to improve the symptoms of Peyronie' s disease (PD) in patients with a curvature deformity of < 30° at the beginning of therapy. Methods & Materials: Sixty-one PD patients were studied. Thirty were randomly assigned to receive verapamil 10 mg/session (Isoptin®, BGP Products, Rome-Italy), (Group 1, median age 56 years, range 49-62), and 31 were randomly assigned to receive hyaluronic acid 8 mg/session (Sinovial®, IBSA, Lodi-Italy) (Group 2, median age 58 years, range 51-56). There were ten sessions, 2 sessions/week for each drug. Each drug was transdermally administered using the hydroelectrophoresis technique and carried out using a Hydro4and apparatus (Swiss4Med SA, Morbio Inferiore, Switzerland). With respect to the efficacy of the drugs studied, the endpoints were: side effects, pain, erectile function, penile deviations and plaque area (cm2) before, and 3 and 6 months after drug administration. The differences were assessed using the Mann-Whitney Rank test (unmatched groups) or using the Wilcoxon Signed Rank test (matched groups). The differences between the groups in terms of side effects were assessed using the chi-square test. Results: No significant difference emerged among the baseline values of the two groups. Pain, erectile function, plaque area and penile deformity significantly improved in both groups after treatment, but a notably higher improvement occurred in the patients in whom hyaluronic acid was administered. Only a few negligible side effects occurred in the Group 1 patients treated with Verapamil, with no significant difference between the groups. Conclusion: Administration of both hyaluronic acid and verapamil using the Hydro4and apparatus is a safe and efficient method for PD therapy. Medkrux 2018-07-11 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion Original Article application/pdf application/xml https://jmrionline.com/jmri/article/view/119 10.15419/jmri.119 Journal of Medical Research and Innovation; Vol 2 No 2 (2018); e000119 2456-8139 eng https://jmrionline.com/jmri/article/view/119/156 https://jmrionline.com/jmri/article/view/119/157 Copyright (c) 2018 Giorgio Cavallini, Carlo Maretti http://creativecommons.org/licenses/by/4.0

oai:ojs2.jmrionline.com:article/121 2018-11-14T08:15:46Z jmri:CR driver

Dyke-Davidoff-Masson Syndrome: A Delayed Diagnosis of an Acquired Variant Kumar, T Seetam Vipul, Abhijit Yadav, Rohtas Dyk-Davidof-Masson Syndrome (DDMS) is an important cause of intractable and drug-resistant seizures. It has varied clinical presentation and history with distinct neuroimaging features. Here, we describe a female patient presented with recurrent intractable convulsion, mental retardation, hemiparesis, and characteristic neuroimaging features of cerebral hemiatrophy, calvarial thickening, and ipsilateral hyperpneumatization of the frontal sinuses which is suggestive of DDMS. Early institution of neuroimaging in patients with intractable epilepsy will make early diagnosis and better outcome. Medkrux 2018-07-03 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion application/pdf application/xml https://jmrionline.com/jmri/article/view/121 10.15419/jmri.121 Journal of Medical Research and Innovation; Vol 2 No 2 (2018); e000121 2456-8139 eng https://jmrionline.com/jmri/article/view/121/143 https://jmrionline.com/jmri/article/view/121/144 Copyright (c) 2018 Journal of Medical Research and Innovation http://creativecommons.org/licenses/by-nc-nd/4.0

oai:ojs2.jmrionline.com:article/122 2018-11-14T08:15:46Z jmri:CR driver

Aneurysmal Bone Cyst of Talus Shrestha, Dhan Bahadur Thapa, Bishnu Babu Maharjan, Dipendra Basnet, Kumar Ghimire, Prabeen Karki, Sijan Aneurysmal bone cyst (ABC) of talus is rare benign, expansile and osteolytic bone growth. Cyst contains bloody fluid lined with variable amount of osteolytic giant cells. This is common in epiphyseal ends of long bone and rare in small bones like talus. Here a 20 years’ male with aneurysmal bone cyst of talus managed with wide intralesional curettage with autologous bone graft mixed with synthetic bone graft been presented. Medkrux 2018-07-05 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion application/pdf application/xml https://jmrionline.com/jmri/article/view/122 10.15419/jmri.122 Journal of Medical Research and Innovation; Vol 2 No 2 (2018); e000122 2456-8139 eng https://jmrionline.com/jmri/article/view/122/145 https://jmrionline.com/jmri/article/view/122/146 Copyright (c) 2018 Journal of Medical Research and Innovation http://creativecommons.org/licenses/by-nc-nd/4.0

oai:ojs2.jmrionline.com:article/125 2019-08-25T16:39:52Z jmri:ABS

oai:ojs2.jmrionline.com:article/126 2019-08-25T16:39:52Z jmri:ABS

oai:ojs2.jmrionline.com:article/127 2019-08-25T16:39:52Z jmri:ABS

oai:ojs2.jmrionline.com:article/128 2019-08-25T16:39:52Z jmri:ABS

oai:ojs2.jmrionline.com:article/130 2018-11-14T08:15:46Z jmri:BVA driver

Developing A Scale for Measuring Perfection Quotient (PQ) to Predict Readiness to Health Behavior Change Sharma, Manoj Kanekar, Amar Lakhan, Ram The concept of perfection quotient (PQ) that imbibes the basics of intelligence quotient (IQ), emotional quotient (EQ), X quotient (XQ) and spiritual dimension has been proposed to measure readiness for individual-level health behavior change. PQ can be defined as a sum total of combined cognitive capacity, balanced emotions, desirable personality traits, and spiritual awareness to meet the best possible success of life goals. The present article reifies this concept into a practical scale that includes the concept of IQ implicitly by developing the scale at less than seventh-grade level. It explicitly operationalizes the concept of EQ through three constructs namely self-awareness, mood management, and self-motivation into a health emotional quotient (HEQ). It also operationalizes the concept of health X quotient (HXQ) through the constructs of cautiousness, independence, and competition with self.  Finally, it operationalizes the concept of health spiritual quotient (HSQ) through the constructs of self-love and love for others around oneself. The summation of HEQ, HXQ, and HSQ yields the PQ score which can range from 0-100 units. It is proposed that score of 0-25 units indicates needing improvement low perfection score; a score of 26-50 units indicates needing improvement small perfection score; a score of 51-75 units indicates moderate perfection score that can be better; a score of 76-100 units indicates high perfection score on the continuum and high readiness for health behavior change. The scale can be freely used by health behavior researchers while providing due credit. Medkrux 2018-06-10 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion application/pdf application/pdf application/xml https://jmrionline.com/jmri/article/view/130 10.15419/jmri.130 Journal of Medical Research and Innovation; Vol 2 No 2 (2018); e000130 2456-8139 eng https://jmrionline.com/jmri/article/view/130/140 https://jmrionline.com/jmri/article/view/130/142 https://jmrionline.com/jmri/article/view/130/152 Copyright (c) 2018 Manoj Sharma, Amar Kanekar, Ram Lakhan http://creativecommons.org/licenses/by/4.0

oai:ojs2.jmrionline.com:article/133 2019-08-25T16:39:52Z jmri:ABS

oai:ojs2.jmrionline.com:article/134 2019-08-25T16:39:52Z jmri:ABS

oai:ojs2.jmrionline.com:article/136 2019-08-25T16:39:52Z jmri:ABS

oai:ojs2.jmrionline.com:article/137 2019-08-25T16:39:52Z jmri:ABS

oai:ojs2.jmrionline.com:article/138 2019-08-25T16:39:52Z jmri:ABS

oai:ojs2.jmrionline.com:article/139 2018-11-14T08:15:46Z jmri:OGA driver

Markers of Poor Prognosis in Non-ST Segment Elevation Acute Coronary Syndromes Without Revascularization: A 3-Year Survival Analysis Parkhomenko, Alexander Dovgan, Natalia Lutay, Yaroslav Kozhukhov, Sergey Introduction: The non-ST elevation acute coronary syndrome (NSTE-ACS) account for more than 50% of the total number of patients with ACS. The mortality rates after NSTEMI are not significantly different when compared with patients with ST-segment elevation myocardial infarction. Aim: The aim of the present study was to investigate whether the assessment of clinical, laboratory and instrumental data during hospital stay provide any additional independent information in predicting the 3-year major cardiac events after NSTE-ACS. Methods: We observed 490 consecutive patients, who were admitted to the emergency cardiology department with NSTE-ACS. The patients' baseline characteristics, blood analysis, left ventricle (LV) and renal function data were assessed and analyzed. The median follow‑up time was 36 months. The endpoint was cardiovascular death. Results: The results of our study show that the risk of cardiovascular death during the three years follow-up after multivariate adjustment increases with older age (> 64 years), history of diabetes, prior myocardial infarction and history of angina pectoris, lower ejection fraction (<50%), degree of myocardial hypertrophy (the thickness of the interventricular septum >1.25 mm) of the LV and the degree of diastolic dysfunction (E-wave deceleration time (DT) < 150 ms), silent myocardial ischemia during first 24-hours, high pulse pressure on Day 1 (>49 mm Hg), glucose level > 7.5 mmol/l on admission and moderate kidney dysfunction (CrCl <60 ml/min). Conclusion: In patients with NSTE-ACS, we report the cardiovascular death risk factors within the 3-year follow-up period in the present study. We thus conclude that it is important to identify the patients with high risk of future cardiovascular complications. Medkrux 2018-07-17 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion Original Article application/pdf application/xml https://jmrionline.com/jmri/article/view/139 10.15419/jmri.139 Journal of Medical Research and Innovation; Vol 2 No 2 (2018); e000139 2456-8139 eng https://jmrionline.com/jmri/article/view/139/158 https://jmrionline.com/jmri/article/view/139/159 Copyright (c) 2018 Alexander Parkhomenko, Natalia Dovgan, Yaroslav Lutay, Sergey Kozhukhov http://creativecommons.org/licenses/by/4.0

oai:ojs2.jmrionline.com:article/141 2018-12-19T18:02:35Z jmri:RV driver

3D Printing and its Future in Medical World Sharma, Sunil Goel, Shakti A. Since the time of its inception, 3D printing has not only fascinated the researchers but also health professionals. Though the process is exciting, it involves meticulous coordination and selection process to achieve a desirable product. This review article discusses about the history of evolution of 3 D printers, their current application and future trends. Emphasis has also been laid to recognize the best suitable product and ways to prevent its misuse. Medkrux 2018-08-27 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion Review Article application/pdf application/xml https://jmrionline.com/jmri/article/view/141 10.15419/jmri.141 Journal of Medical Research and Innovation; Vol 3 No 1 (2019); e000141 2456-8139 eng https://jmrionline.com/jmri/article/view/141/160 https://jmrionline.com/jmri/article/view/141/164 Copyright (c) 2018 Sunil Sharma, Shakti A. Goel http://creativecommons.org/licenses/by/4.0

oai:ojs2.jmrionline.com:article/142 2018-12-19T18:02:35Z jmri:CR driver

Acute intermittent porphyria with posterior reversible encephalopathy syndrome in pregnancy: a case report Arora, Hemalata Baheti, Gaurav Jain, Ankur Bhalsod, Maulik Mehta, Varshil Background: The porphyrias are a clique of metabolic disorders caused by a faulty heme-synthesis process. The acute intermittent porphyria (AIP) is the most common type of porphyria. It results from a decrease in the porphobilinogen deaminase enzyme levels (PBG-D) which plays a vital role in the hepatic phase of heme synthesis. Case Report: A 26-years-old lady without any co-morbidity or prior history of any disease came with acute abdominal pain. The causes of acute abdominal pain such as the ectopic pregnancy and other causes were excluded after investigations. She was eventually diagnosed with AIP and managed accordingly. The findings of MRI Brain were suggestive of posterior reversible encephalopathy syndrome (PRES). The patient was treated with hematin, glucose and symptomatic treatment were also given. However, the patient had persistent autonomic dysfunction and hyponatremia, followed by cardiac arrest and death. Conclusion: The diagnosis of AIP is often missed in cases of an acute abdominal pain in pregnant women. Early diagnosis of AIP during pregnancy followed by proper management is associated with favourable maternal and foetal outcome. Delay in the management leads to the worse outcomes like maternal morbidity, mortality or foetal loss. Medkrux 2018-09-19 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion application/pdf application/xml https://jmrionline.com/jmri/article/view/142 10.15419/jmri.142 Journal of Medical Research and Innovation; Vol 3 No 1 (2019); e000142 2456-8139 eng https://jmrionline.com/jmri/article/view/142/162 https://jmrionline.com/jmri/article/view/142/165 Copyright (c) 2018 Hemalata Arora, Gaurav Baheti, Ankur Jain, Maulik Bhalsod, Varshil Mehta http://creativecommons.org/licenses/by/4.0

oai:ojs2.jmrionline.com:article/144 2018-11-14T08:15:46Z jmri:ACK

Editors and Reviewers Acknowledgement, 2(2), July-December, 2018 Team, Editorial The Journal of Medical Research and Innovation would like to thank each and every one who has helped us to review and edit the articles. As a small token of appreciation, we would like to mention the names of all the editors and reviewers in random order here who have edited or reviewed the articles for the July, 2018 issue. The list will be updated as when more reviewers review the articles. Editors 1) Varshil Mehta2) Shakti Goel3) Krutarth Shah 4) Sergey Kozhukhov   Reviewers 1) Shakti Goel 2) Varshil Mehta 3) Mykola Khaitovych 4) Rahul Kotian 5) Hira Lal 6) Prashant Pradhan 7) Pravin Padalkar 8) Saumya Agarwal 9) Mathew Asare 10) Edith Claros 11) Surya Parajuli 12) Rajesh Sharawat 13) Nishu Tyagi 14) Pradosh Sarangi 15) Deepak Jain 16) Hamsini C 17) Vicky Varghese 18) Nishtha Agarwal 19) Ishpreet Biji 20) Tushar Kunder 21) Rushi Solanki 22) Suvendu Maji 23) Sergey Kozhukhov 24) Shaunak Ajinkya Medkrux 2018-07-26 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion https://jmrionline.com/jmri/article/view/144 10.15419/jmri.144 Journal of Medical Research and Innovation; Vol 2 No 2 (2018); e000144 2456-8139 Copyright (c) 2018 Editorial Team http://creativecommons.org/licenses/by/4.0

oai:ojs2.jmrionline.com:article/147 2018-12-19T18:02:35Z jmri:OGA driver

A study of patient satisfaction level in inpatient spine department of a tertiary care multi-speciality hospital Srivastava, Narayani Goel, Shakti Background: Patient satisfaction at spine surgery centers is a matter of concern. In specialized surgeries like spine, the satisfaction of a patient is not merely because of surgical outcomes but also empathy of doctor, rehabilitation programs and friendliness of the hospital. Aims and Objectives: This study aims to investigate the prognosis and satisfaction level of patients/relatives operated with spinal surgery. This shall not only help the spinal hospitals to know the ways to improve the patient outcome but methods to provide better services. Material and methods: The study was conducted by carrying out survey amongst 39 patients and their relatives at inpatient department of spine surgical unit by using structured questionnaire and analysing the data using SPSS software. The patients were examined before and after surgery and their VAS (Visual Analogue Score) and ODI (Oswestry Disability Index) were also documented. The SERVQUAL methodology was also studied to understand if it could be implemented in the study to understand better and make the study more conclusive.   Results: The study composed of 39 individuals with an average age of 75.6 +-10.2 years.39 percent of the study group were females and 61 percent males. The ODI score in post-operative stage (18.97+_12.97) was significantly reduced as compared to pre-operative stage (76.66+-17.23) (p<0.05). The VAS score in post-operative stage (1.48 +-1.8) was also significantly reduced as compared to pre-operative stage ( 9.51 +- 0.22) (p<0.05). Ninety-Two percent people were satisfied with the housekeeping services while Ninety-Eight percentage were satisfied with the medical care provided. Ninety-five percentage of people were satisfied by the behaviour of staff and nurses. The nursing department, cleanliness and behaviour of the doctor satisfied 90 percent, 87 and 84.59 percent. The admission and reception satisfied only 66 percentage . The SERVQUAL study was not incorporated because the questionnaire designed through this methodology requires to be administrated by face to face interviews along with moderate to large sample size for statistical reliability.   Conclusion: This study has clearly shown that satisfactory results are obtained after spine surgery. However, the  results are better when performed by a fellowship trained surgeon. Moreover, doctors who spend time in explaining the ailments and possible outcomes to the patients have more satisfactory results. A caring attitude of the staff and empathy in interaction makes a lot of difference in the success of the practice of a surgeon. Medkrux 2018-10-11 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion Original Article application/pdf application/xml https://jmrionline.com/jmri/article/view/147 10.15419/jmri.147 Journal of Medical Research and Innovation; Vol 3 No 1 (2019); e000147 2456-8139 eng https://jmrionline.com/jmri/article/view/147/168 https://jmrionline.com/jmri/article/view/147/169 Copyright (c) 2018 Narayani Srivastava and Shakti Goel http://creativecommons.org/licenses/by/4.0

oai:ojs2.jmrionline.com:article/148 2018-12-19T18:02:35Z jmri:News driver

Ayushman Bharat Initiative: India’s Answer to Universal Health-Care Mehta, Varshil Abstract not available. Medkrux 2018-09-17 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion Editorial application/pdf application/xml https://jmrionline.com/jmri/article/view/148 10.15419/jmri.148 Journal of Medical Research and Innovation; Vol 3 No 1 (2019); e000148 2456-8139 eng https://jmrionline.com/jmri/article/view/148/161 https://jmrionline.com/jmri/article/view/148/163 Copyright (c) 2018 Varshil Mehta http://creativecommons.org/licenses/by/4.0

oai:ojs2.jmrionline.com:article/149 2021-07-13T11:16:36Z jmri:OGA driver

Cadaveric Study of Lung Anatomy: A Surgical Overview Ganapathy, Arthi Tandon, Rati Baxla, Monica Kaler, Saroj Background: Thorough knowledge of variations in lung anatomy is of prime significance during surgical procedures of lungs. Arrangement of structures in lung hilum act as a guide in performing such procedures. Normal pattern of arrangement of hilar structures in right lung is eparterial bronchus, pulmonary artery, hyparterial bronchus and pulmonary veins from above downwards. In left lung it is pulmonary artery, principal bronchus and pulmonary vein from above downwards. Arrangement of hilar structures from anterior to posterior in both lungs is pulmonary vein, pulmonary artery and principal bronchus. Aim: To report variations in hilar anatomy (arrangement and number) of lungs. Methods and Material: 75 adult formalin fixed cadaveric lungs from department of Anatomy AIIMS New Delhi were observed for variations in lobar anatomy. Arrangement of pulmonary hilar structures observed and variations recorded. Results: Among 75 adult lung specimens observed, 36 were right and rest left lung. Normal pattern of arrangement of hilar structures was seen in 22 right and 23 left lungs. Rest of the lung specimens (14 Right and 16 Left) showed variations in hilar anatomy. Some of them showed alterations in sequence of arrangement of pulmonary artery, pulmonary veins, bronchus and others in number of these structures. Seven right lung specimens showed only 2 lobes with an oblique fissure dividing them and one left lung showed 3 lobes. Conclusion: Alterations in pattern of arrangement of structures in lung hilum are quite frequent. A compromise in knowledge of such variations will result in inadvertent intraoperative complications. Medkrux 2018-11-11 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion Original Article application/pdf application/xml https://jmrionline.com/jmri/article/view/149 10.32892/jmri.149 Journal of Medical Research and Innovation; Vol 3 No 1 (2019); e000149 2456-8139 eng https://jmrionline.com/jmri/article/view/149/171 https://jmrionline.com/jmri/article/view/149/174 Copyright (c) 2018 Arthi Ganapathy, Rati Tandon, Monica Baxla, Saroj Kaler http://creativecommons.org/licenses/by/4.0

oai:ojs2.jmrionline.com:article/152 2019-08-25T16:39:52Z jmri:ABS

oai:ojs2.jmrionline.com:article/153 2019-08-25T16:39:52Z jmri:ABS

oai:ojs2.jmrionline.com:article/154 2019-08-25T16:39:52Z jmri:ABS

oai:ojs2.jmrionline.com:article/155 2019-08-25T16:39:52Z jmri:ABS

oai:ojs2.jmrionline.com:article/156 2019-08-25T16:39:52Z jmri:ABS

oai:ojs2.jmrionline.com:article/157 2019-08-25T16:39:52Z jmri:ABS

oai:ojs2.jmrionline.com:article/158 2021-07-13T11:16:36Z jmri:OGA driver

Impact of Continuous Professional Education on Leadership for Rehabilitation Professionals in Bangladesh: A Pilot Study Hossain, K M Amran Nazim, Anawarul Quader Hossain, Md. Shahadat Haque, Md. Obaidul Hossain, Mohammad Anwar Hossain, Md. Zahid Ahmed, Md Shahoriar Background: In healthcare and rehabilitation profession, continuous professional education (CPE) is deemed as an essential tool by institutions, regulatory bodies and organizations. It is considered to be a safeguard to professional practice to ensure patient safety and efficient service delivery. Leadership program is an emerging subject that integrates technical, management and leadership skill that found indispensable to enhance ultimate professional development. Objective: The purpose of this article is to explore the potential impact of CPE on leadership training for rehabilitation professionals in Bangladesh. Methodology: This pilot study was a mixed methods study. 20 rehabilitation professionals participated in the study. Quantitative data were collected by structured questionnaire and qualitative data were obtained by face to face video recording interviews. Quantitative data were analyzed by Statistical Package for the Social Sciences (SPSS)   and thematic analysis was considered for qualitative data. Result: Study findings showed that 95% of the participants (n=19) were in their 2nd to 3rd decade of life, there mean age were 26 and male participation (n=12) were higher than female (n=8). Highest academic qualification was master’s degree and none of the participants attended leadership training before. Overall objective, planning and atmosphere of the training course, quality of trainers and time management seemed effective and satisfactory to the participants they agreed with. Leadership qualities and elements have profound impacts on knowledge and attitude towards positivity in performing professional duties and Responsibilities. The training also enhances motivation to be a skilled professional in clinical practice, also encourages serving with outmost excellence towards patients or clients. Conclusion: The study demonstrates that education on leadership to professionals have an impact on motivation and positivity towards developing technical, management and professional skills. The study may have impact on developing diverse qualities of a professional in personal and organizational perspective; this can be explored by continuing education on leadership and evaluation of the behavioral changes, professional and management skills in rehabilitation professionals’ serving in an organization in longer run. Medkrux 2018-12-20 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion Original Article application/pdf text/xml https://jmrionline.com/jmri/article/view/158 10.32892/jmri.158 Journal of Medical Research and Innovation; Vol 3 No 1 (2019); e000158 2456-8139 eng https://jmrionline.com/jmri/article/view/158/175 https://jmrionline.com/jmri/article/view/158/178 Copyright (c) 2018 K M Amran Hossain, Anawarul Quader Nazim, Md. Shahadat Hossain, Md. Obaidul Haque, Mohammad Anwar Hossain, Md. Zahid Hossain, Md Shahoriar Ahmed http://creativecommons.org/licenses/by/4.0

oai:ojs2.jmrionline.com:article/159 2021-07-13T11:16:35Z jmri:ACK driver

Editors and Reviewers Acknowledgement, 3(1), January-June, 2019 Team, Editorial The Journal of Medical Research and Innovation would like to thank each and every one who has helped us to review and edit the articles. As a small token of appreciation, we would like to mention the names of all the editors and reviewers in random order here who have edited or reviewed the articles for the January, 2019 issue. Editors Varshil Mehta Shakti Goel Sojib Bin Zaman   Reviewers (List includes reviewers of both accepted and rejected papers) Shyam Vora Ankit Nayak Hemant Chouhan Ruby Aikat Pravin Padalkar Nishu Tyagi Rajesh Sharawat Harsha Makwana Chinmay Jani Nishtha Agarwal Jitendra Singh Vishal Kamra Sakshi Shandilya Dyuti Mittal Mehrdad Ghorbanlou SSSN Rajasekhar Sharmin Majumder Raihan Khan Ishpreet Biji Rahul Kotian Medkrux 2018-12-21 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion application/pdf https://jmrionline.com/jmri/article/view/159 10.32892/jmri.159 Journal of Medical Research and Innovation; Vol 3 No 1 (2019); e000159 2456-8139 eng https://jmrionline.com/jmri/article/view/159/177 Copyright (c) 2018 Editorial Team http://creativecommons.org/licenses/by/4.0

oai:ojs2.jmrionline.com:article/161 2019-08-26T14:59:20Z jmri:OGA driver

Knowledge, Attitude and Practice of Preventing the Occurrence of Work-Related Musculoskeletal Disorders Among Doctors in University of Port-Harcourt Teaching Hospital Ephraim-Emmanuel, Benson Chukwunweike Ogbomade, Ronami Idumesaro, Blackman Nabai Ugwoke, Innocent Background: Musculoskeletal disorders affecting medical personnel should never be treated lightly. It has thus become necessary to strictly infuse ergonomics in medical practice in order to tackle the occurrence of musculoskeletal system disorders. This would ensure better productivity among the medical personnel. This research was conducted to determine the knowledge, attitude and practice of the prevention of work-related musculoskeletal disorders among doctors working at the University of Port-Harcourt Teaching Hospital.Methods: A descriptive, cross-sectional study design was employed in carrying out this study among doctors working at the University of Port Harcourt Teaching Hospital. Multistage sampling was utilized in selecting a sample population of 223 doctors for this study. Data collection was done using a semi-structured self-administered questionnaire. Ethical approval to conduct this study was gotten from the University of Port-Harcourt research ethics committee. Consent, confidentiality, privacy and beneficence were ensured in this study. For test of associations, statistical significance was set at 0.05.Results: Majority of the respondents had good knowledge and attitude towards musculoskeletal disorders’ prevention at work. The practice of ergonomic principles was however not satisfactory. Occurrence of work-related musculoskeletal disorders among study respondents was significantly associated with the knowledge and practice of ergonomic principles required to prevent the occurrence of these disorders.Conclusion: Despite the significant proportion of doctors in this study having good knowledge and attitude towards prevention of musculoskeletal system disorders at work, only few of these doctors satisfactorily practiced the necessary preventive measures necessary to prevent these disorders. This inadvertently resulted in the high prevalence of these disorders found in this study. It is recommended that a re-orientation of doctors to be more involved in the actual application of ergonomics while working no matter the compulsion or desire to get the work done should be done. Medkrux 2019-02-17 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion Original Article application/pdf text/xml https://jmrionline.com/jmri/article/view/161 10.32892/jmri.161 Journal of Medical Research and Innovation; Vol 3 No 2 (2019); e000161 2456-8139 eng https://jmrionline.com/jmri/article/view/161/185 https://jmrionline.com/jmri/article/view/161/188 Copyright (c) 2019 Benson Chukwunweike Ephraim-Emmanuel, Ronami Ogbomade, Blackman Nabai Idumesaro, Innocent Ugwoke http://creativecommons.org/licenses/by/4.0

oai:ojs2.jmrionline.com:article/163 2021-07-13T11:16:35Z jmri:COR driver

Correction to: Impact of Continuous Professional Education on Leadership for Rehabilitation Professionals in Bangladesh: A Pilot Study Hossain, K M Nazim, Anawarul Quader Hossain, Md. Shahadat Haque, Md. Obaidul Hossain, Mohammad Anwar Hossain, Md. Zahid Ahmed, Md Shahoriar In the publication of this article, the abstract, full-text of the article and the author's affiliations had some mistakes with regards to the writing/language. The abstract, full-text and the affiliations of the authors has now been updated in the original article. The authors declare that the correction does not change the results or conclusion of this paper. Medkrux 2019-01-02 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion application/pdf https://jmrionline.com/jmri/article/view/163 10.32892/jmri.163 Journal of Medical Research and Innovation; Vol 3 No 2 (2019); e000163 2456-8139 eng https://jmrionline.com/jmri/article/view/163/176 Copyright (c) 2019 K M Hossain, Anawarul Quader Nazim, Md. Shahadat Hossain, Md. Obaidul Haque, Mohammad Anwar Hossain, Md. Zahid Hossain, Md Shahoriar Ahmed http://creativecommons.org/licenses/by/4.0

oai:ojs2.jmrionline.com:article/164 2019-08-26T14:59:20Z jmri:OGA driver

Metformin Inhibits Growth of Breast Cancer Cell T47D through Decreasing Expression of Protein P53, BCL2 and Cyclin D1 Rangkuti, Irma Yanti Hasibuan, Poppy Anjelisa Zaitun Widyawati, Tri Siregar, Yahwardiah Breast cancer is a disease that afflicts women only 0.5 to 1 % are male breast cancers.Breast cancer has several variants and requires a different therapeutic approach, and until now the therapy has not been satisfactory due to the emergence of resistance. Metformin as the main choice drug type 2 diabetes mellitus which is known to have a cytotoxic effect for breast cancer. This study aimed to analyze metformin cytotoxic mechanisms covering the cell cycle , apoptosis, expression of p53, bcl-2 and cyclin D1 T47D cells which exposed to metformin HCl. The study was conducted invitro on T47D breast cancer cells which exposed to metformin concentrations of 1738.2 µg / mL and 3476.4 µg / mL and doxorubicin concentrations of 0.1µg / mL and 0.2µg / mL for 24 hours. Cell cycle testing and apoptosis using the flowsitometry method and expression test of p53 protein, bcl-2 dancycline D1 in T47D cells with immunocytochemistry. Data was analyzed by one way Anova with Bonferroni's advanced test. The results showed that metformin inhibited the G0-G1 phase of the T47D cell cycle, triggered T47D cell apoptosis, significantly reduced p53, bcl-2 and cyclin D1 protein expression (p <0.05). Conclusion of the study, metformin inhibits T47D cells through inhibition of the cell cycle G0-G1 phase, reducing protein expression p53, bcl-2 and cyclin D1. Medkrux 2019-04-04 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion Original Article application/pdf text/xml https://jmrionline.com/jmri/article/view/164 10.32892/jmri.164 Journal of Medical Research and Innovation; Vol 3 No 2 (2019); e000164 2456-8139 eng https://jmrionline.com/jmri/article/view/164/189 https://jmrionline.com/jmri/article/view/164/190 Copyright (c) 2019 Irma Yanti Rangkuti, Poppy Anjelisa Zaitun Hasibuan, Tri Widyawati, Yahwardiah Siregar http://creativecommons.org/licenses/by/4.0

oai:ojs2.jmrionline.com:article/165 2019-08-26T14:59:20Z jmri:OGA driver

Psychosocial determinants of communication satisfaction in racially concordant and discordant patient-physician interactions Assari, Shervin Introduction: Although both socioeconomic and race- related factors both influence quality of medical encounters, it is not known how these effects differ between racially concordant and discordant medical visits. Current study investigated psychosocial determinants of physician visit satisfaction of Black adults based on racial concordance of the medical encounter. Materials and Methods: Data came from the Detroit Area Study (DAS), a community survey of adults in Michigan, United States. The current analysis included 336 Black individuals who had visited a White (n = 191) or a Black (n=145) physician in the last year. Outcome was satisfaction with the quality of communication with the doctor. Demographics (age and gender), socioeconomic staus (education and income), psychosocial factors (control beliefs and social support), race related factors (having a close White friend, negative attitudes about Blacks, discrimination), and health status (chronic disease count, self-rated health, and distress) of the patient as well as race of the doctor were measured. We used multi-group structural equation modeling (SEM) for data analysis, where the two groups were racially concordant (those who met a Black physician) and racially discordant (those who met a White physician) visits.   Results: Satisfaction with physician visit was lower in racially discordant than racially concordant encounters. In racially concordant visits, high education was associated with higher satisfaction, however, racial discrimination was associated with lower satisfaction. In racially discordant visits (i.e. with a White doctor), having a White friend as well as high sense of control were associated with a higher satisfaction, while negative attitudes about Blacks was associated with lower level of satisfaction. Conclusions: Racially concordant and discordant visits have different satisfaction levels. Racially concordant and discordant visits also have different predictors of communication satisfaction among Black patients. Socioeconomic status as well as racial attitudes and experiences impact quality of communication of the Black patients with their doctors, however, these effects depend on the race of the doctor. Medkrux 2019-06-07 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion Original Article application/pdf text/xml https://jmrionline.com/jmri/article/view/165 10.32892/jmri.165 Journal of Medical Research and Innovation; Vol 3 No 2 (2019); e000165 2456-8139 eng https://jmrionline.com/jmri/article/view/165/198 https://jmrionline.com/jmri/article/view/165/199 Copyright (c) 2019 Shervin Assari http://creativecommons.org/licenses/by/4.0

oai:ojs2.jmrionline.com:article/170 2021-07-13T11:16:35Z jmri:News driver

What we look for in an article before accepting? Mehta, Varshil Medkrux 2019-02-05 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion Editorial text/xml application/pdf https://jmrionline.com/jmri/article/view/170 10.32892/jmri.170 Journal of Medical Research and Innovation; Vol 3 No 2 (2019); e000170 2456-8139 eng https://jmrionline.com/jmri/article/view/170/179 https://jmrionline.com/jmri/article/view/170/180 Copyright (c) 2019 Varshil Mehta http://creativecommons.org/licenses/by/4.0

oai:ojs2.jmrionline.com:article/172 2019-08-26T14:59:20Z jmri:News driver

Non-Spinal Causes of Back Pain: An ‘undiagnosed’ diagnosis Goel, Shakti Low back pain is a common ailment affecting individuals all around the globe. Majority of Disability Adjusted Life Years lost amongst working population is due to low back pain. Though majority of surgeons/physicians keep only spinal causes in mind while treating such an ailments, a number of other causes exist for such a pathology. This editorial aims to make the readers aware about such non spinal causes of low back pain. Medkrux 2019-02-17 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion Editorial application/pdf text/xml https://jmrionline.com/jmri/article/view/172 10.32892/jmri.172 Journal of Medical Research and Innovation; Vol 3 No 2 (2019); e000172 2456-8139 eng https://jmrionline.com/jmri/article/view/172/184 https://jmrionline.com/jmri/article/view/172/187 Copyright (c) 2019 Shakti Goel http://creativecommons.org/licenses/by/4.0

oai:ojs2.jmrionline.com:article/178 2019-08-26T14:59:20Z jmri:CR driver

Steroid Pulse Therapy in the Management of Neuro-psychiatric Manifestations in an Atypical Presentation of Typhoid Fever Jain, Ankur Baheti, Gaurav The Typhoid fever often presents with a variety of clinical symptoms and numerous systemic complications. Neurological complications of enteric fever are relatively insidious and rare and many times late and often undiagnosed complication of typhoid fever which can change the course of illness. This is a case of blood culture-proven typhoid fever with neuropsychiatric manifestations responded well with appropriate antibiotics and steroid pulse therapy (1 gram Methylprednisolone for 3 days). Medkrux 2019-07-01 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion application/pdf text/xml https://jmrionline.com/jmri/article/view/178 10.32892/jmri.178 Journal of Medical Research and Innovation; Vol 3 No 2 (2019); e000178 2456-8139 eng https://jmrionline.com/jmri/article/view/178/193 https://jmrionline.com/jmri/article/view/178/194 Copyright (c) 2019 Ankur Jain; Gaurav Baheti, Varshil Mehta http://creativecommons.org/licenses/by/4.0

oai:ojs2.jmrionline.com:article/179 2019-08-26T14:59:20Z jmri:OGA driver

Unequal Effects of Educational Attainment on Workplace Exposure to Second-Hand Smoke by Race and Ethnicity; Minorities’ Diminished Returns in the National Health Interview Survey (NHIS) Assari, Shervin Bazargan, Mohsen Background: One of the mechanisms by which high educational attainment promotes populations’ health is through reducing exposure to environmental risk factors such as second-hand smoke. Minorities’ Diminished Returns theory, however, posits that the protective effect of educational attainment may be smaller for racial and ethnic minority individuals particularly Blacks and Hispanics compared to Whites. Aims: To explore racial and ethnic differences in the association between educational attainment and second-hand smoke exposure at work in a national sample of American adults. Methods: Data came from the National Health Interview Survey (NHIS 2015), a cross-sectional study that included 15,726 employed adults. The independent variable was educational attainment, the dependent variables were any and daily second-hand smoke exposure at workplace, age and gender were covariates, and race and ethnicity were the moderators. Results: Overall, higher educational attainment was associated with lower odds of any and daily second-hand smoke exposure at work. Race and ethnicity both interacted with educational attainment suggesting that the protective effects of educational attainment on reducing the odds of any and daily second-hand smoke exposure at work are systemically smaller for Blacks and Hispanics than Whites. Conclusions: In the United States, race and ethnicity bound the health gains that follow educational attainment. While educational attainment helps individuals avoid environmental risk factors such as second-hand smoke, this is more valid for Whites than Blacks and Hispanics. The result is additional risk of cancer and tobacco related disease in highly educated Blacks and Hispanics. The results are important given racial and ethnic minorities are the largest growing section of the US population. We should not assume that educational attainment is similarly protective across all racial and ethnic groups. In this context, educational attainment may increase, rather than reduce, health disparities. Medkrux 2019-07-24 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion Original Article application/pdf text/xml https://jmrionline.com/jmri/article/view/179 10.32892/jmri.179 Journal of Medical Research and Innovation; Vol 3 No 2 (2019); e000179 2456-8139 eng https://jmrionline.com/jmri/article/view/179/201 https://jmrionline.com/jmri/article/view/179/202 Copyright (c) 2019 Shervin Assari, Mohsen Bazargan http://creativecommons.org/licenses/by/4.0

oai:ojs2.jmrionline.com:article/180 2019-08-26T14:59:20Z jmri:RV driver

Transcatheter aortic valve replacement in Bicuspid Aortic Valve Disease: An Insight Mehta, Varshil Nalluri, Nikhil Kumar, Varun Patel, Nileshkumar Atti, Varunsiri Narula, Arvin Cohen, Mauricio As per the current scenario, role of Transcatheter aortic valve replacement (TAVI) is controversial in bicuspid aortic valve stenosis. All the randomized clinical trials comparing outcomes of TAVI with surgery till date, have excluded patients with bicuspid aortic valve. Some of the observational studies have reported outcomes of TAVI in bicuspid aortic valve stenosis patients who are not surgical candidate. The recent advances in TAVI and its expansion into intermediate groups, which includes younger age groups sparks a debate on the efficacy and safety of TAVI in Bicsuspid aortic valve (BAV). The purpose of the present article is to review the available literature regarding the feasibility, safety and outcomes of TAVI in bicuspid aortic valve stenosis. Medkrux 2019-07-16 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion Review Article application/pdf text/xml https://jmrionline.com/jmri/article/view/180 10.32892/jmri.180 Journal of Medical Research and Innovation; Vol 3 No 2 (2019); e000180 2456-8139 eng https://jmrionline.com/jmri/article/view/180/195 https://jmrionline.com/jmri/article/view/180/197 Copyright (c) 2019 Varshil Mehta, Nikhil Nalluri, Varun Kumar, Nileshkumar Patel, Varunsiri ATti, Arvin Narula, Mauricio Cohen http://creativecommons.org/licenses/by/4.0

oai:ojs2.jmrionline.com:article/183 2020-02-08T10:31:45Z jmri:OGA driver

Neuroticism polygenic risk score predicts 20-year burden of depressive symptoms for Whites but not Blacks Assari, Shervin Javanbakht, Arash Saqib, Mohammed Helmi, Hamid Bazargan, Mohsen Smith, Jennifer A. Background. Black-White differences are reported in social, psychological, behavioral, medical, and biological correlates of depression. This study was conducted to compare Black and White older adults for the association between neuroticism polygenic risk score (N-PRS) and chronicity of depressive symptoms over 20 years. Methods. Data came from the Health and Retirement Study (HRS), 1990 – 2012, a nationally representative sample of Americans above age 50. Current analysis followed 9,249 individuals (7,924 Whites and 1,325 Blacks) for up to 22 years. Depressive symptoms were measured every two years between 1992 and 2012 using the 8-item Center for Epidemiological Studies-Depression Scale (CES-D-8). The independent variable was N-PRS. The dependent variable was average depressive symptoms between 1992 and 2012. Linear regression was used for data analysis. Results. In the pooled sample, higher N-PRS was associated with higher average depressive symptoms over the 20-year follow up period [b=0.01, 95%CI=0.00 to 0.04], net of all covariates. We also found an interaction between race and N-PRS [b=-0.02, 95%CI=-0.03 to 0.00], suggesting a stronger effect of N-PRS on 20-year average depressive symptoms for Whites than Blacks. Based on our race-specific linear regression models, higher N-PRS was associated with higher depressive symptoms from 1992 to 2012 for Whites [b=0.01, 95%CI=0.01 to 0.02] but not Blacks [b=0.00, 95%CI=-0.02 to 0.02]. Conclusion. Black and White older adults may differ in the salience of the existing N-PRS for depressive symptoms, which better reflects the burden of depression for Whites than Blacks. This may be because the existing PRSs are derived from mostly or exclusively White samples, limiting their applicability in other race groups. Racial variation in psychosocial, clinical, and biological correlates of depression needs further research. Medkrux 2019-08-26 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion Original Article application/pdf text/xml https://jmrionline.com/jmri/article/view/183 10.32892/jmri.183 Journal of Medical Research and Innovation; Vol 4 No 1 (2020); e000183 2456-8139 eng https://jmrionline.com/jmri/article/view/183/205 https://jmrionline.com/jmri/article/view/183/208 Copyright (c) 2019 Shervin Assari http://creativecommons.org/licenses/by/4.0

oai:ojs2.jmrionline.com:article/185 2020-02-08T10:31:45Z jmri:OGA driver

Race, Educational Attainment, and E-Cigarette Use Assari, Shervin Mistry, Ritesh Bazargan, Mohsen Background: Although higher educational attainment lowers high-risk behaviors such as substance use, according to the Minorities’ Diminished Returns theory, the effect of educational attainment may be smaller for Blacks than Whites. Aims: To explore the racial differences in the link between educational attainment and electronic cigarettes (e-cigarettes). Methods: We used the Health Information National Trends Survey (HINTS) data. This national survey was conducted in 2017 and included 2,277 American adults composed of 1,868 White and 409 Black individuals. Educational attainment was the independent variable. E-cigarette use (lifetime) was the dependent variables. Age and gender were the covariates. Race was the effect modifier. Results: In the overall sample, a higher level of education attainment was linked to lower odds of e-cigarette use (OR = 0.76, 95% CI =0.61-0.95). Race showed a significant interaction with educational attainment on the outcome (OR = 1.63, 95% CI =1.04-2.56), suggesting a weaker negative association between high educational attainment and e-cigarette use for Blacks than Whites. In race-stratified logistic regression models, high educational attainment was inversely associated with risk of e-cigarette use for Whites but not Blacks. Conclusion: Educational attainment shows a stronger effect on e-cigarette use in White than Black Americans. Medkrux 2019-09-14 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion Original Article application/pdf text/xml https://jmrionline.com/jmri/article/view/185 10.32892/jmri.185 Journal of Medical Research and Innovation; Vol 4 No 1 (2020); e000185 2456-8139 eng https://jmrionline.com/jmri/article/view/185/207 https://jmrionline.com/jmri/article/view/185/211 Copyright (c) 2019 Shervin Assari, Ritesh Mistry, Mohsen Bazargan http://creativecommons.org/licenses/by/4.0

oai:ojs2.jmrionline.com:article/187 2020-02-08T10:31:45Z jmri:CS driver

To Evaluate Anti-HLA Antibodies Sensitization in Pre- and Post-renal Transplant Patient’s Serum: A Retrospective Case Series Agarwal, Nishtha Goswami, Sanjeev Introduction: In India, patients of renal failure are dependent on live related or unrelated donor. Because of poor financial condition patients do not go for DSA (Donor Specific Antibody) detection using Luminex. In absence of screening of de-novo production of DSA and don’t get proper management. As a result of which patient undergo acute rejection. Case Series: Here we are presenting 5 acute rejection cases comparing there DSA in pre-transplant and post-transplant sera using solid-phase assays.5 renal transplanted patients undergone acute and hyperacute rejection (Banff's classification) were considered for presented case series. Collected serum (pre and post-transplant on day of rejection) from each patient was subjected to detection of anti-HLA antibody using Luminex-PRA. Conclusion: Presence of donor-specific anti-HLA antibody with their titer was detected in pre and post-transplant serum. It is found that the strength of DSA is directly proportional to graft life. Medkrux 2019-08-31 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion application/pdf https://jmrionline.com/jmri/article/view/187 10.32892/jmri.187 Journal of Medical Research and Innovation; Vol 4 No 1 (2020); e000187 2456-8139 eng https://jmrionline.com/jmri/article/view/187/206 Copyright (c) 2019 Nishtha Agarwal, Sanjeev Goswami http://creativecommons.org/licenses/by/4.0

oai:ojs2.jmrionline.com:article/190 2021-07-13T11:16:32Z jmri:FWD driver

Program schedule of 3rd International Conference on Clinical Orthopedics & Spine Biomechanics Team, Editorial The program schedule of 3rd International Conference on Clinical Orthopedics & Spine Biomechanics held at ISIC, New Delhi, India. Medkrux 2019-08-26 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion application/pdf https://jmrionline.com/jmri/article/view/190 10.32892/jmri.190 Journal of Medical Research and Innovation; Vol 3 No S1 (2019); S1-S8 2456-8139 eng https://jmrionline.com/jmri/article/view/190/203 Copyright (c) 2019 Editorial Team http://creativecommons.org/licenses/by/4.0

oai:ojs2.jmrionline.com:article/191 2021-07-13T11:16:31Z jmri:ABS driver

Abstracts Presented at 3rd International Conference on Clinical Orthopedics & Spine Biomechanics Team, Editorial Abstracts Presented at 3rd International Conference on Clinical Orthopedics & Spine Biomechanics held at ISIC, New Delhi, India. Medkrux 2019-08-26 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion Non-peer reviewed application/pdf https://jmrionline.com/jmri/article/view/191 10.32892/jmri.191 Journal of Medical Research and Innovation; Vol 3 No S1 (2019); S9-S22 2456-8139 eng https://jmrionline.com/jmri/article/view/191/204 Copyright (c) 2019 Editorial Team http://creativecommons.org/licenses/by/4.0

oai:ojs2.jmrionline.com:article/192 2021-07-13T11:16:29Z jmri:OGA driver

Influence of Varying Doses and Duration of Dietary Nitrates from Beetroot Juice on Sprint Performance in U.S. Army ROTC Cadets: A pilot study Melton, Michael Kandiah, Jayanthi Objective: Assess the effects of varying levels and duration of dietary nitrate supplementationfrom beetroot juice (BR) on sprint performance in army ROTC cadets. Methods: Army Reserve Officer Training Corps (ROTC) cadets were randomly assigned to oneof three treatment groups: control (CON); low beetroot juice dose (BR1); and high BR juice –BR2. For 0, 6 and 15 days nitrate consumption from BR groups were as follows: CON receivedone 16.9 oz. bottle of apple juice (0 mg NO 3 -); BR1 received one can of BR juice (300 mg, 4.84mmol NO 3 -), and BR2 received 2 cans (16.8 oz.) BR (600 mg, 9.68 mmol NO 3 -). One week priorto the study, each cadet completed body composition measurements, predicted aerobic capacitymeasurements, and nutritional analysis via two 24-hour dietary recalls. Differences in primarymeasures (distance covered in the Yo-Yo IR1) were analyzed with two-way repeated measuresANOVA tests both between groups (CON, BR1, BR2) and within groups (0, 6, and day 15).Descriptive statistics and frequency counts were run on all remaining variables with a one-wayANOVA or t-test, including maximal heart rate during the YoYo IR1, dietary compliance, dailyblood pressure, juice compliance, and conditioning work-outs Results: A dose-related enhancement with BR was observed; the data trended towardssignificance even in this small sample. A t-test revealed that there was a significant difference insprint performance by males and females overall at days 0, 6, 15 (p = 0.025, p = 0.005, p =0.004, respectively). Conclusion: A single (300 mg, 4.84 mmol NO 3 ) or double (600 mg, 9.68 mmol NO 3 -) daily doseconsumption of BR appears to benefit ROTC cadets in athletic performance. Daily consumptionof BR benefitted ROTC males more than females. Results suggest BR supplementation could beadvantageous for sprint performance when administered for a longer duration (> 15 days). Medkrux 2019-12-28 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion Original Article application/pdf text/xml https://jmrionline.com/jmri/article/view/192 10.32892/jmri.192 Journal of Medical Research and Innovation; Vol 4 No 1 (2020); e000192 2456-8139 eng https://jmrionline.com/jmri/article/view/192/210 https://jmrionline.com/jmri/article/view/192/217 Copyright (c) 2019 Michael Melton and Jayanthi Kandiah http://creativecommons.org/licenses/by/4.0 f0618408ad2b6ed8658ad605222a0ef4