Cadaveric Study of Lung Anatomy: A Surgical Overview
Summary: Thorough knowledge of variations in lung anatomy is of prime significance during surgical procedures of lungs. Arrangement of structures in lung hilum act as a guide in performing such procedures. Normal pattern of arrangement of hilar structures in right lung is ...
Markers of Poor Prognosis in Non-ST Segment Elevation Acute Coronary Syndromes Without Revascularization: A 3-Year Survival Analysis
The non-ST elevation acute coronary syndrome (NSTE-ACS) account for more than 50% of the total number of patients with ACS. The mortality rates after NSTEMI are not significantly different when compared with...
Hydroelectrophoresis for Transdermal Administration of Verapamil or of Hyaluronic Acid in Peyronie's Disease: A Prospective, Open Label, Multicenter Study
To assess the efficacy of a new electromotive system for the transcutaneous delivery of verapamil or of hyaluronic acid to improve the symptoms of Peyronie' s disease (PD) in patients with a curvature deformity of < 30Â°...
Developing A Scale for Measuring Perfection Quotient (PQ) to Predict Readiness to Health Behavior Change
The concept of perfection quotient (PQ) that imbibes the basics of intelligence quotient (IQ), emotional quotient (EQ), X quotient (XQ) and spiritual dimension has been proposed to measure readiness for...
Demographic Profile of Spinal Cord Injury Patients Admitted in a Rehabilitation Centre: An Observational Study from Bangladesh
Spinal cord injury (SCI) is a life threating condition which has a profound impact in the morbidity and mortality. SCI causes lifetime sufferings and mostly occur among the young adults. Not only in Bangladesh but also worldwide, SCI is a devastating and burdensome condition. This research was conducted to see the demographic profile of SCI patients in Bangladesh...
ISIC, IIT Delhi, Hamburg University and University of Toledo presents in association with JMRI
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Metformin Inhibits Growth of Breast Cancer Cell T47 through Decreasing Expression of Protein P53, BCL2 and Cyclin D1
Summary: Breast cancer is a disease that afflicts women only 0.5 to 1 % are male breast cancers.Breast cancer has several variants and requires a different therapeutic approach, and until now the therapy has not been satisfactory due to the emergence of resistance. Metformin as the main choice drug type 2 diabetes mellitus which is known to have a cytotoxic effect for breast cancer. This study aimed to analyze metformin cytotoxic mechanisms covering the cell cycle , apoptosis, expression of p53, bcl-2 and cyclin D1 T47D cells which exposed to metformin HCl. The study was conducted invitro on T47D breast cancer cells which exposed to metformin concentrations of 1738.2 µg / mL and 3476.4 µg / mL and doxorubicin concentrations of 0.1µg / mL and 0.2µg / mL for 24 hours. Cell cycle testing and apoptosis using the flowsitometry method and expression test of p53 protein, bcl-2 dancycline D1 in T47D cells with immunocytochemistry. Data was analyzed by one way Anova with Bonferroni's advanced test. The results showed that metformin inhibited the G0-G1 phase of the T47D cell cycle, triggered T47D cell apoptosis, significantly reduced p53, bcl-2 and cyclin D1 protein expression (p <0.05). Conclusion of the study, metformin inhibits T47D cells through inhibition of the cell cycle G0-G1 phase, reducing protein expression p53, bcl-2 and cyclin D1.
Knowledge, Attitude and Practice of Preventing the Occurrence of Work-Related Musculoskeletal Disorders Among Doctors in University of Port-Harcourt Teaching Hospital
Summary: Despite the significant proportion of doctors in this study having good knowledge and attitude towards prevention of musculoskeletal system disorders at work, only few of these doctors satisfactorily practiced the necessary preventive measures necessary to prevent these disorders. This inadvertently resulted in the high prevalence of these disorders found in this study. It is recommended that a re-orientation of doctors to be more involved in the actual application of ergonomics while working no matter the compulsion or desire to get the work done should be done.
Non-Spinal Causes of Back Pain: An ‘undiagnosed’ diagnosis
Summary: Low back pain is a common ailment affecting individuals all around the globe. Majority of Disability Adjusted Life Years lost amongst working population is due to low back pain. Though majority of surgeons/physicians keep only spinal causes in mind while treating such an ailments, a number of other causes exist for such a pathology. This editorial aims to make the readers aware about such non spinal causes of low back pain.
Correction to: Impact of Continuous Professional Education on Leadership for Rehabilitation Professionals in Bangladesh: A Pilot Study
Summary: In the publication of this article, the abstract, full-text of the article and the author's affiliations had some mistakes with regards to the writing/language. The abstract, full-text and the affiliations of the authors has now been updated in the original article. The authors declare that the correction does not change the results or conclusion of this paper.
Editors and Reviewers Acknowledgement, 3(1), January-June, 2019
Summary: The Journal of Medical Research and Innovation would like to thank each and every one who has helped us to review and edit the articles. As a small token of appreciation, we would like to mention the names of all the editors and reviewers in random order here who have edited or reviewed the articles for the January, 2019 issue.
Impact of Continuous Professional Education on Leadership for Rehabilitation Professionals in Bangladesh: A Pilot Study
K M A.,
Summary: In healthcare and rehabilitation profession, continuous professional education (CPE) is deemed as an essential tool by institutions, regulatory bodies and organizations. It is considered to be a safeguard to professional practice to ensure patient safety and efficient service delivery. Leadership program is an emerging subject that integrates technical, management and leadership skill that found indispensable to enhance ultimate professional development.
Cadaveric Study of Lung Anatomy: A Surgical Overview
Summary: Thorough knowledge of variations in lung anatomy is of prime significance during surgical procedures of lungs. Arrangement of structures in lung hilum act as a guide in performing such procedures. Normal pattern of arrangement of hilar structures in right lung is eparterial bronchus, pulmonary artery, hyparterial bronchus and pulmonary veins from above downwards. In left lung it is pulmonary artery, principal bronchus and pulmonary vein from above downwards. Arrangement of hilar structures from anterior to posterior in both lungs is pulmonary vein, pulmonary artery and principal bronchus.
Retracted : Comparative Evaluation Of Efficacy of Omeprazole versus Lansoprazole for Relief of Functional Dyspepsia: A Systematic Review
Summary: Functional dyspepsia (FD) is defined as a condition chronically presenting symptoms centered in the upper abdomen, such as epigastric pain or discomfort, in the absence of any organic, systemic, or metabolic disease that is likely to explain the symptoms. Proton pump inhibitors are main line agents to treat functional Dyspepsia. Omeprazole is conventional PPI and Lansoprazole is a new PPI both are said to be effective option to treat functional dyspepsia in individual trials.
Retracted : A study of cases of Diphtheria diagnosed at Civil Hospital, Ahmedabad, India
Summary: Most of the vaccine preventable diseases have shown a decline with advent of National immunization schedule but Diphtheria is still present in some region of India. The purpose of this study is to diagnose cases of Diphtheria.
Retracted : Comparative Study of Non-Descent Vaginal Hysterectomy with Abdominal Hysterectomy
Summary: 1) To compare safety and operative complications in abdominal versus vaginal routes of hysterectomy. 2) To compare the length of stay in hospital with regard to the route of hysterectomy. 3) To compare the postoperative morbidity in abdominal versus vaginal routes of hysterectomy.
Retracted : Comparative Study of Oral Hygiene Among Urban and Urban Slum Dwellers of Ahmedabad
Summary: Aims and Objectives: To compare the oral hygiene practices and study the proportion of dental problems among urban and urban slum areas.
Retracted : Comparative Evaluation of Efficacy of Ritodrine Versus Nifedipine in Prevention of Preterm Labour in Direct Head to Head Randomized Control Trials: A Systematic Review
Summary: Aims and Objectives: To compare the efficacy of ritodrine versus nifedipine in prevention of preterm labour at day two and seven.
Retracted : Comparative Evaluation of Efficacy and Safety of Monotherapy with Carbamazepine and Phenytoin In Epilepsy : A Meta-Analysis
Summary: Aims and Objectives
A study of patient satisfaction level in inpatient spine department of a tertiary care multi-speciality hospital
Summary: Patient satisfaction at spine surgery centers is a matter of concern. In specialized surgeries like spine, the satisfaction of a patient is not merely because of surgical outcomes but also empathy of doctor, rehabilitation programs and friendliness of the hospital.
Acute intermittent porphyria with posterior reversible encephalopathy syndrome in pregnancy: a case report
Summary: The porphyrias are a clique of metabolic disorders caused by a faulty heme-synthesis process. The acute intermittent porphyria (AIP) is the most common type of porphyria. It results from a decrease in the porphobilinogen deaminase enzyme levels (PBG-D) which plays a vital role in the hepatic phase of heme synthesis.